教學

目前開授科目：

分子生物學技術、分子癌症學、細胞生物學原理與技術、細胞分子生物學特論、普通生物學(含實驗)

專長與研究

專長：

腫瘤生物學、細菌致病機轉、分子醫學、生物標記、治療標靶

研究領域：

針對各種腫瘤或致病細菌篩選有潛力的生物標記以：(1)探討其分子機制; (2)確認其在診斷、預後與標靶治療的應用。

專利：

1. METHOD FOR THE TREATMENT OF ATG4-RELATED DISORDERS-美國US20190183860. Lee-Wei Yang, Chih-Wen Shu, Pei-Feng Liu, Kun-Lin Tsai.

榮譽

榮譽：

教學

● 課程評量績優-高雄醫學大學(112學年)

● 課程評量績優-高雄醫學大學(111學年)

●課程評量績優-高雄醫學大學(110學年)

● 教師教學評量績優-高雄醫學大學(108學年)

● 課程評量績優-高雄醫學大學(108學年)

研究

● 教師研究論文獎-高雄醫學大學(112學年)

●教師研究論文獎-高雄醫學大學(111學年)

● 研究績優教師優秀論文獎-高雄醫學大學(110學年)

● 教師研究論文獎-高雄醫學大學(110學年)

● 教師研究論文獎-高雄醫學大學(109學年)

● 研究績優教師優秀論文獎-高雄醫學大學(108學年)

● 教師研究論文獎-高雄醫學大學(108學年)

● 年輕研究學者獎助金-嚴慶齡醫學基金會(2018)

服務/輔導

● 指導大專生榮獲大學碩博士生研究計畫成果壁報論文競賽自然組優等-高雄醫學大學(114學年)

● 校級績優導師(生命科學院)-高雄醫學大學(113學年)

● 指導暑期大專生專題研究成果報告績優-高雄醫學大學 (113學年)

● 指導暑期大專生榮獲專題研究成果論文壁報競賽自然組最佳口頭發表-高雄醫學大學(113學年)

● 指導暑期大專生榮獲專題研究成果論文壁報競賽自然組特優-高雄醫學大學(113學年)

● 指導暑期大專生榮獲專題研究成果論文壁報競賽自然組優等-高雄醫學大學(113學年)

● 指導大專生榮獲學生論文壁報競賽生醫與生技組優等-高雄醫學大學生命科學院(112學年)

● 指導大專生榮獲學生論文壁報競賽生醫與生技組佳作-高雄醫學大學生命科學院(112學年)

● 指導暑期大專生專題研究成果報告績優-高雄醫學大學 (112學年)

● 校級績優導師(生命科學院)-高雄醫學大學(111學年)

● 指導暑期大專生榮獲壁報論文競賽自然組優等-高雄醫學大學(111學年)

● 指導大專生榮獲研究生論文壁報競賽生醫與生技組優等-高雄醫學大學生命科學院(111學年)

● 指導大專生榮獲研究生論文壁報競賽生醫與生技組佳作-高雄醫學大學生命科學院(111學年)

● 指導大專生國科會研究計畫-高雄醫學大學(110學年)

● 校級績優輔導導師(職涯組)-高雄醫學大學(110學年)

● 指導暑期大專生榮獲壁報論文競賽自然組特優-高雄醫學大學(110學年)

● 指導大專生榮獲研究生論文壁報競賽生醫與生技組佳作-高雄醫學大學生命科學院(110學年)

● 指導研究生榮獲學生論文壁報競賽生醫與生技組第三名-高雄醫學大學生命科學院(109學年)

● 指導大專生榮獲學生論文壁報競賽生醫與生技組佳作-高雄醫學大學生命科學院(109學年)

● 指導暑期大專生榮獲壁報論文競賽自然組優等-高雄醫學大學(109學年)

● 校級績優導師(生命科學院)-高雄醫學大學(108學年)

期刊論文

期刊論文：(^#: first author; *: corresponding author)

2025

1.CW Shu, CH Chang, HH Wang, PF Liu^* (co-corresponding author), YF Chang^*(2025) Transmembrane Proteins (TMEMs) in Cancer: Insights from Mechanism to Clinical Impact. Open Biology (Accepted, IF:3.6, 129/319, BIOCHEMISTRY & MOLECULAR BIOLOGY)

2.CW Shu, CF Chen, CC Chang, CH Lee, HH Tseng, KF Hu, YH Chou, CL Chen, WC Wang^*, PF Liu^* (2025) The reciprocal regulation between TNF-α and autophagy for oral squamous cell carcinoma progression. Journal of Oral Pathology & Medicine (Accepted, IF: 2.3, 53/162, DENTISTRY, ORAL, SURGERY &MEDICINE)

3.  KF Hu, JL Yeh, YC Lin, PF Liu, YH Chou^*, CJ Tseng^* (2025) The correlation between body mass index and the effectiveness of non-surgical periodontal treatment in Taiwan population. Clinical Oral Investigations 29(12):596. (IF: 3.1, 30/162, DENTISTRY, ORAL, SURGERY &MEDICINE)

4.PF Liu^{# *}, SW Yang^#, WH Yang, SF Huang, CY Tsai, CJ Hsu, HH Tseng, CH Lee, CW Shu^* (2025) Autophagy Protease ATG4D Facilitates Proliferation and Malignancy of Osteosarcoma Cells. FABES Journal 39(17):e70990. (IF: 4.2, 17/107 (<20%), Biology)

5.Liu HP, Tai SB, Jiang JL, Tey SF, Liu PF, Lin MW, Wu SC, Chen YC, Chen CL^* (2025) Epac (RAPGEF3) promotes betaglycan expression to mediate ciprofloxacin-induced suppression of cancer cell migration and metastasis: Mechanistic insights and drug repurposing potential. Biomedicine & Pharmacotherapy 189:118261. (IF: 7.5, 19/352 (<10%), PHARMACOLOGY & PHARMACY)

6.  Hu KF, Chou YH, Lan CC, Ho PS, Liu PF^* (co-corresponding author), Tseng CJ^* (2025) Greater bone regeneration required for implants following periodontal extraction: a retrospective cross-sectional study. BMC Oral Health 18;25(1):586. (IF: 3.1, 30/162(<20%), DENTISTRY, ORAL SURGERY & MEDICINE)

7.YC Tseng^#, PF Liu^# (co-first author), YR Chen, WH Yang, CC Chang, HW Chang, CH Lee, YG Goan^*, CW Shu^*(2025) Elevated neuregulin-1 expression modulates tumor malignancy and autophagy in esophageal squamous cell carcinoma. International Journal of Molecular Medicine 55(4):62. (IF:5.8, 39/195 (20%), MEDICINE, RESEARCH & EXPERIMENTAL)

8.HL Chou^#, IL Lin^#, YT Chen, WT Chang, A Yu, WC Chen, CY Wu, SJ Chiou, CW Shu, CC Chiu^*, PF Liu^*(2025) Aniline TFPA enhances camptothecin-induced anti-NSCLC by modulating oxidative stress and impairing autophagy. Cancer Cell International 25:81. (IF: 6.0, 55/326 (<20%), ONCOLOGY)

9.  JR Weng^#, CW Shu^#, CC Chang^#, YC Wu, HC Yang, CH Lee, HU Dahms, WY Lin, CL Chen, PF Liu^* (2025) Aglaia elliptifolia leaf extract inhibits autophagy-related 4B protease and suppresses malignancies of colorectal cancer cells. Environmental Toxicology 40 (4):549–562. (IF: 3.2, 42/131, WATER RESOURCES)

10.  KF Hu^#, CW Shu^#, CF Chen, CH Lee, HC Kung, YH Chou, CL Chen, PF Liu^* (2025) Regulation of exosomal miR-320d/FAM49B axis by guanylate binding protein 5 promotes cell growth and tumor progression in oral squamous cell carcinoma. Journal of Oral Pathology & Medicine 54(5):298-311. (IF: 2.3, 53/162, DENTISTRY, ORAL, SURGERY &MEDICINE)

11.  M Jadhao, SK Hsu, D Deshmukh, PF Liu, SF Weng, YF Chen, CY Lee, CY Wang, EM Tsai, LF Wang^*, CC Chiu^*(2025) Prolonged DEHP exposure enhances the stemness and metastatic potential of TNBC in an MSI2-dependent manner. International Journal of Biological Sciences 21(4):1705-172. (IF: 10, 26/319 (<10%), BIOCHEMISTRY & MOLECULAR BIOLOGY)

12.  Wang YC, Tai SB, Yang JL, Liu PF, Sung PJ, Su JH, Chen CL (2025). Analysis of Cembrane-Type Diterpenoids from Cultured Soft Coral Sclerophytum flexibile for Inhibition of TGF-β-Induced IL-6 Secretion in Inflammation-Associated Cancer. International Journal of Molecular Sciences. 26(23):11280. (IF: 4.9, 72/319, BIOCHEMISTRY & MOLECULAR BIOLOGY)

13.  YH Chou, WL Hsiao, CJ Chen, YC Lin, PF Liu, KF Hu^*, Cheng CW^* (2025). Association between prosthesis contour and peri-implantitis in patients compliant with supportive periodontal therapy: A retrospective cohort study. Journal of Prosthodontic Research 69(1):68-75. (IF:3.4, 25/162 (<20%), DENTISTRY, ORAL SURGERY & MEDICINE)

2024

14.  CF Chen, CM Chen^*, WC Huang, SH Liu, LL Wang, PF Liu, PH Chen^* (2024). The use of customized 3D-printed mandibular prostheses with pressure-reducing device: a clinical trial. Head & Neck 46:1614–1624. (IF: 2.2, 15/67, OTORHINOLARYNGOLOGY)

15.  CF Chen, WC Huang, SH Liu, LL Wang, PF Liu, Chen PH, Chen CM^* (2024). Use of customized 3-dimensional printed mandibular prostheses with a dental implant pressure-reducing device in mandibular body defect: a finite element study performing multiresponse surface methodology. Journal of Dental Sciences 19(1):502-514. (IF: 3.1, 30/162 (<20%), DENTISTRY, ORAL SURGERY & MEDICINE)

2023

16.  KF Hu^#, CW Shu^#, CH Lee, CJ Tseng, YH Chou, PF Liu^* (2023). Comparative clinical significance and biological roles of PFKFB family members in oral squamous cell carcinoma. Cancer Cell International 23(1):257. (IF: 6.0, 55/326, ONCOLOGY)

17.  JL Yang^#, WL Lin^#, SB Tai, YS Ciou, CL, Chung, JJ Chen, PF Liu, MW Lin, CL Chen^* (2023) Suppression of TGFβ-induced interleukin-6 secretion by sinulariolide from soft corals through attenuation of the p38–NF-κB pathway in carcinoma cells. International Journal of Molecular Sciences. 24 (14), 11656. (IF: 4.9, 72/319, BIOCHEMISTRY & MOLECULAR BIOLOGY)

18.  YH Chou^#, YJ Chen^#, CP Pan, WH Yen, PF Liu, IJ Feng, YC Lin^*, KF Hu^*(2023). Prevalence of peri-implantitis after alveolar ridge preservation at periodontitis and nonperiodontitis. Clinical Implant Dentistry and Related Research 25(6):1000-1007. (IF: 4.0, 14/162 (<10%), DENTISTRY, ORAL SURGERY & MEDICINE)

19.  SW Lin, KF Hu^*, YC Lin, PF Liu, YH Chou^* (2023) Changes in alveolar bone width around maxillary implants, as determined through cone beam computed tomography based on bony landmarks: a preliminary study. Clinical Implant Dentistry and Related Research. 25(5):861-870. (IF: 4.0, 14/162 (<10%), DENTISTRY, ORAL SURGERY & MEDICINE)

20.  YF Chang^#, HH Wang^#, CW Shu, WL Tsai, CH Lee, CL Chen, PF Liu^* (2023) TMEM211 promotes tumor progression and metastasis in colon cancer. Current Issues in Molecular Biology 45(6), 4529-4543. (IF: 3.0, 169/319, BIOCHEMISTRY & MOLECULAR BIOLOGY)

21.  PF Liu and YF Chang^* (2023) The controversial roles of areca nut: medicine or toxin? International Journal of Molecular Sciences 24(10), 8996. (IF: 4.9, 72/319, BIOCHEMISTRY & MOLECULAR BIOLOGY)

22.  CC Tseng^#, CC Hung^#, CW Shu, CH Lee, CF Chen, MS Kuo, YY Kao, CL Chen, LP Ger, PF Liu^*(2023) The clinical and biological effects of receptor expression-enhancing protein 6 in tongue squamous cell carcinoma. Biomedicines 11(5), 1270. (IF: 3.9, 88/352, PHARMACOLOGY & PHARMACY)

23.  WH Hu^#, TT Liu^#, PF Liu, P Morgan, IL Lin, WL Tsai, YY Cheng, AT Hsieh, TH Hu, CW Shu^* (2023) ATG4B and pS383/392-ATG4B serve as potential biomarkers and therapeutic targets of colorectal cancer. Cancer Cell International 23(1):63. (IF: 6.0, 55/326 (<20%), ONCOLOGY)

2022

24.  PF Liu^#, CF Chen^#, LP Ger, WL Tsai, HH Tseng, CH Lee, WH Yang, CW Shu* (2022) MAP3K11 facilitates autophagy activity and is correlated with malignancy of oral squamous cell carcinoma. Journal of Cellular Physiology 237(11):4275-4291. (IF: 4.0, 14/87(<20%), PHYSIOLOGY)

25.  PF Liu^#, AA Farooqie^#, SY Peng, TJ Yu, HU Dahms, C H Lee, JY Tang, SC Wang, CW Shu^*, HW Chang^* (2022) Regulatory effects of noncoding RNAs on the interplay of oxidative stress and autophagy in cancer malignancy and therapy. Seminars in Cancer Biology 83:269-282. (IF: 15.7, 18/326 (<10%), ONCOLOGY)

26.  YH Chou, YC Lin, MH Lee, YT Huang, PF Liu, CL Huang, KF Hu^* (2022) Highly educated patients have lower dental compliance during the covid-19 pandemic: an observational study. BMC Oral Health 22(1):284. (IF: 3.1, 30/162(<20%), DENTISTRY, ORAL SURGERY & MEDICINE)

27.  WL Tsai^*, JS Cheng, PF Liu, TH Chang, WC Sun, WC Chen, CW Shu^* (2022) Sofosbuvir induces gene expression for promoting cell proliferation and migration of hepatocellular carcinoma cells. Aging-US 14(14):5710-5726. (2023 IF: 3.9, 24/74, GERIATRICS & GERONTOLOGY)

28.  KC Chang, PF Liu, CH Chang, YC Lin, YJ Chen, CW Shu^* (2022) The interplay of autophagy and oxidative stress in the pathogenesis and therapy of retinal degenerative diseases. Cell and Bioscience 12(1):1. (IF: 6.2, 50/319 (<20%), BIOCHEMISTRY & MOLECULAR BIOLOGY)

2021

29.  PF Liu, CW Shu, CH Lee, HC Sie, HH Liou, JT Cheng, LP Ger, CL Chen, CC Chen^*, CF Chen^* (2021) Clinical significance and the role of guanylate-binding protein 5 in oral squamous cell carcinoma. Cancers (Basel) 13(16): 4043. (IF: 4.4, 85/326, ONCOLOGY)

30.  PF Liu, CW Shu, HC Yang, CH Lee, HH Liou, LP Ger, YD Tony Tzeng^*, WC Wang^* (2021) Combined Evaluation of MAP1LC3B and SQSTM1 for biological and clinical significance in ductal carcinoma of breast cancer. Biomedicines 9(11):1514. (IF: 3.9, 88/352, PHARMACOLOGY & PHARMACY)

31.  YK Tseng, CF Chen, CW Shu, CH Lee, YT Chou, YJ Li, HH Liou, JT Cheng, CL Chen, LP Ger, PF Liu^* (2021) Effect of EGFR on SQSTM1 expression in malignancy and tumor progression of oral squamous cell carcinoma. International Journal of Molecular Sciences 22(22):12226. (IF: 4.9, 72/319, BIOCHEMISTRY & MOLECULAR BIOLOGY)

32.  JT Cheng^#, PF Liu^# (co-first author), HC Yang, SJ Huang, M Griffithg, P Morgang, CW Shu^* (2021) Tumor susceptibility gene 101 facilitates rapamycin-induced autophagic flux in neuron cells. Biomedicine & Pharmacotherapy 134:111106. (IF: 7.5, 19/352 (<10%), PHARMACOLOGY & PHARMACY)

33.  CC Chang^#, CC Chiu^#, PF Liu, CH Wu, YC Tseng, CH Lee, CW Shu^* (2021) Kinome-wide siRNA screening identifies DYRK1B as a potential therapeutic target for triple-negative breast cancer cell. Cancers 13(22):5779. (IF: 4.4, 85/326, ONCOLOGY)

34.  WH Hu^#, WC Yang^#, PF Liu, TT Liu, P Morgan, WL Tsai, HW Pan, CH Lee CW Shu^* (2021) Clinicopathological Association of autophagy related 5 protein with prognosis of colorectal cancer. Diagnostics 11(5):782. (IF: 3.3, 57/332(<20%), MEDICINE, GENERAL & INTERNAL)

35.  CY Huang^#, JL Yang^#, JJ Chen^#, SB Tai, YH Yeh, PF Liu, MW Lin, CL Chung, CL Chen* (2021) Fluoroquinolones suppress TGF-β and PMA-Induced MMP-9 production in cancer cells: implications in repurposing quinolone antibiotics for cancer treatment. International Journal of Molecular Sciences 22(21):11602. (IF: 4.9, 72/319, BIOCHEMISTRY & MOLECULAR BIOLOGY)

36.  KF Hu, SW Lin, YC Lin, JH Jeng, YT Huang, PF Liu, CJ Tseng^*, YH Chou^* (2021) Using cone-beam computed tomography to assess changes in alveolar bone width around dental implants at native and reconstructed bone sites: a retrospective cohort study. Journal of Personalized Medicine 11(10):1011. (2023 IF: 3.0, 59/329(<20%), MEDICINE, GENERAL & INTERNAL)

37.  CW Shu^#, JR Weng^#, HW Chang, PF Liu, JJ Chen, CC Peng, JW Huang, WY Lin, CY Yen^* (2021) Tribulus Terrestris fruit extract inhibits autophagic flux to diminish cell proliferation and metastatic characteristics of oral cancer cells. Environmental Toxicology 36(6):1173-1180. (IF: 3.2, 42/131, WATER RESOURCES)

38.  CY Huang^#, CL Chung^#, TH Hu, JJ Chen, PF Liu, CL Chen^* (2021) Recent progress in TGF-β inhibitors for cancer therapy. Biomedicine & Pharmacotherapy 134:111046. (IF: 7.5, 19/352(<10%), PHARMACOLOGY & PHARMACY)

2020

39.  PF Liu, CF Chen, CW Shu, HM Chang, CH Lee, HH Liou, LP Ger, CL Chen, BH Kang^* (2020) UBE2C is a potential biomarker for tumorigenesis and prognosis in tongue squamous cell carcinoma. Diagnostics 2020, 10(9):674. (IF: 3.3, 57/332(<20%), MEDICINE, GENERAL & INTERNAL)

40.  PF Liu^*, HC Chen, CW Shu, HC Sie, CH Lee, HH Liou, JT Cheng, KW Tsai, LP Ger (2020) Guanylate-binding protein 6 is a novel biomarker for tumorigenesis and prognosis in tongue squamous cell carcinoma. Clinical Oral Investigations 24(8):2673-2682. (IF: 3.1, 30/162 (<20%), DENTISTRY, ORAL, SURGERY &MEDICINE)

41.  HC Chen^#, YK Tseng^#, CW Shu, TY Fu, HH Liou, CH Huang, CC Chen, JS Wang, PC Wu, LP Ger, WC Hung, PF Liu^* (2020) Prognostic role of RECK in pathological outcome-dependent buccal mucosa squamous cell carcinoma. Oral Diseases 2020; 26(1):62-71. (IF: 2.9, 37/162, DENTISTRY, ORAL, 

  SURGERY &MEDICINE)

42.  BH Kang^#, CW Shu^#, JK Chao, CH Lee, TY Fu, HH Liou, LP Ger, PF Liu^* (2020) HSPD1 repressed E-cadherin expression to promote cell invasion and migration for poor prognosis in oral squamous cell carcinoma. Scientific Reports 10(1):1829. (IF: 3.9, 25/135(<20%), MULTIDISCIPLINARY SCIENCES)

2019

43.  PF Liu, HC Chen, JS Cheng, WL Tsai, HP Lee, SC Wang, WH Peng, CH Lee, LP Ger, CW Shu^* (2019) Association of ATG4B and phosphorylated ATG4B proteins with tumorigenesis and prognosis in oral squamous cell carcinoma. Cancers (Basel) 11(12): 1854. (IF: 4.4, 85/326, ONCOLOGY)

44.  YG Goan, PF Liu, HW Chang, HC Chen, WC Chen, SM Kuo, CH Lee, CW Shu^* (2019) Kinome-wide screening with small interfering RNA identified polo-like kinase 1 as a key regulator of proliferation in oral cancer cells. Cancers (Basel) 11(8):1117. (IF: 4.4, 85/326, ONCOLOGY)

45.  HC Chen^#, YK Tseng^#, CW Shu, TJ Weng, HH Liou, LM Yen, IC Hsieh, CC Wang, PC Wu, YL Shiue, TY Fu, KW Tsai, LP Ger^*, PF Liu^*(2019) Differential clinical significance of COL5A1 and COL5A2 in tongue squamous cell carcinoma. Journal of Oral Pathology & Medicine 48(6):468-476. (IF: 2.3, 53/162, DENTISTRY, ORAL, SURGERY &MEDICINE)

46.  JS Cheng^#, WL Tsai^#, PF Liu^# (co-first author), YG Goan, CW Lin, HH Tseng, CH Lee, CW Shu^* (2019) The MAP3K7-mTOR axis promotes the proliferation and malignancy of hepatocellular carcinoma cells. Frontiers in Oncology 9:474. (IF: 3.3, 123/326, ONCOLOGY)

47.  HW Chang^#, PF Liu^# (co-first author), WL Tsai, WH Hu, YC Hu, HC Yang, WY Lin, JR Weng, CW Shu^* (2019) Xanthium strumarium fruit extract inhibits ATG4B and diminishes the proliferation and metastatic characteristics of colorectal cancer cells. Toxins 11(6):313. (IF: 4.0, 26/106, TOXICOLOGY)

2018

48.  HY Chang, YK Tseng, YC Chen, CW Shu, MI Lin, HH Liou, TY Fu, YC Lin, LP Ger, MH Yeh^*, PF Liu^*(2018) High snail expression predicts a poor prognosis in breast invasive ductal carcinoma patients with HER2/EGFR-positive subtypes. Surgical Oncology-Oxford 27(2):314-320. (IF: 2.4, 78/312, SURGERY)

49.  PF Liu^#, KL Tsai^#, CJ Hsu^#, WL Tsai, JS Cheng, HW Chang, CW Shiau, YG Goan, HH Tseng, CH Wu, JC Reed, LW Yang, CW Shu^* (2018) Drug repurposing screening identifies tioconazole as an ATG4 inhibitor that suppresses autophagy and sensitizes cancer cells to chemotherapy. Theranostics 8(3): 830-845. (IF: 13.3, 7/195(<5%), MEDICINE, RESEARCH & EXPERIMENTAL)

50.  PF Liu, Y Wang, RG Ulrich, CW. Simmons, JS. VanderGheynst, RL Gallo, CM Huang^* (2018) Leaf-encapsulated vaccines: agroinfiltration and transient expression of the antigen staphylococcal endotoxin B in radish leaves. Journal of Immunology Research 2018:3710961. (IF: 3.6, 79/183, IMMUNOLOGY)

51.  PF Liu^#, HW Chang^#, JS Cheng, HP Lee, CY Yen, WL Tsai, JT Cheng, YJ Li, WC Huang, CH Lee, LP Ger, CW Shu^* (2018) MAPLC3B and SQSTM1 modulated autophagy for tumorigenesis and prognosis in certain subsites of oral squamous cell carcinoma. Journal of Clinical Medicine 7(12):478. (IF: 2.9, 65/332. (<20%), MEDICINE, GENERAL & INTERNAL)

52.  YD Tony Tzeng^#, PF Liu^# (co-first author), JY Li, LF Liu, SY Kuo, CW Hsieh, CH Lee, CH Wu, M Hsiao, HT Chang, CW Shu^* (2018) Kinome-wide siRNA screening identifies Src-enhanced resistance of chemotherapeutic drugs in triple-negative breast cancer cells. Frontiers in Pharmacology 2018; 9:1285. (IF: 4.8, 51/352 (<20%), PHARMACOLOGY & PHARMACY)

2017

53.  PF Liu^#, CJ Hsu^#, WL Tsai, JS Cheng, JJ Chen, IF Huang, HH Tseng, HW Chang*, CW Shu^* (2017) Ablation of ATG4B suppressed autophagy and activated AMPK for cell cycle arrest in cancer cells.  Cellular Physiology and Biochemistry 44(2):728-740. (IF:2.0, 57/87, PHYSIOLOGY).

54.  PF Liu, YC Hu, BH Kang, YK Tseng, PC Wu, CC Liang, YY Hou, TY Fu, HH Liou, IC Hsieh, LP Ger*, CW Shu^*(2017) Expression levels of cleaved Caspase-3 and Caspase-3 in tumorigenesis and prognosis of oral tongue squamous cell carcinoma. PLoS One 12(7):e0180620. (IF: 2.6, 44/135, MULTIDISCIPLINARY SCIENCES)

55.  PF Liu^#, BH Kang^#, YM Wu, JH Sun, LM Yen, TY Fu, YC Lin, HH Liou, YS Lin, HC Sie, IC Hsieh, YK Tseng, CW Shu, YD Hsieh, LP Ger^* (2017) Vimentin is a potential prognostic factor for tongue squamous cell carcinoma among five epithelial–mesenchymal transition-related proteins. PLoS One 12(6):e0178581 PLoS One 12(7):e0180620. (IF: 2.6, 44/135, MULTIDISCIPLINARY SCIENCES)

56.  PF Liu, Y Wang, YT Liu, CM Huang^* (2017) Vaccination with killed but metabolically active E. coli over-expressing hemagglutinin elicits neutralizing antibodies to H1N1 swine origin influenza A virus. Journal of Nature and Science 3(2):e317.

57.  Huang JS^#, Yang CM^#, Wang JS, Liou HH, Hsieh IC, Li GC, Huang SJ, Shu CW, Fu TY, Lin YC, Ger LP^*, PF Liu^* (2017) Caspase-3 expression in tumorigenesis and prognosis of buccal mucosa squamous cell carcinoma. Oncotarget 8(48):84237-84247. (2016 IF: 5.168, 44/217, ONCOLOGY)

58.  HH Tseng, YK Tseng, JJ You, BH Kang, TH Wang, CM Yang, HC Chen, HH Liou, PF Liu, LP Ger^*, KW Tsai^* (2017) Next-generation sequencing for microRNA Profiling: microRNA-21-3p promotes oral cancer metastasis. Anticancer Research 37(3):1059-1066. (IF: 1.7, 259/326, ONCOLOGY)

2016

59.  TY Fu^#, CN Wu^#, HC Sie, JT Cheng, YS Lin, HH Liou, YK Tseng, CW Shu, KW Tsai, LM Yen, HW Tseng, CJ Tseng, LP Ger^*, PF Liu^* (2016) Subsite-specific association of DEAD Box RNA helicase DDX60 with the development and prognosis of oral squamous cell carcinoma. Oncotarget 7(51):85097-85108. (2016 IF: 5.168, 44/217, ONCOLOGY)

60.  CW Shu, HT Chang, CS Wu, CH Chen, S Wu, Chang HW, Kuo SY, Fu E, PF Liu^* (co-corresponding author), Hsieh YD^* (2016) RelA-mediated BECN1 expression is required for reactive oxygen species-induced autophagy in oral cancer cells exposed to low-power laser irradiation. PLoS One 11(9):e0160586. (IF: 2.6, 44/135, MULTIDISCIPLINARY SCIENCES)

61.  HW Chen, PF Liu, YT Liu, S Kuo, XQ Zhang, RT Schooley, H Rohde, RL Gallo, CM Huang^* (2016)

 Nasal commensal Staphylococcus Epidermidis counteracts influenza virus. Scientific Reports 6:27870.

  (IF: 3.9, 25/135(<20%), MULTIDISCIPLINARY SCIENCES)

62.  CM Yang, TH Wang, HC Chen, SC Li, MC Lee, HH Liou, PF Liu, YK Tseng, YL Shiue, LP Ger, KW Tsai^* (2016) Aberrant DNA hypermethylation-silenced SOX21-AS1 gene expression and its clinical importance in oral cancer. Clinical Epigenetics 8:129. (IF: 4.4, 34/191 (<20%), GENETICS &HEREDITY)

63.  YY Ho, JJ You, CM Yang, HW Pan, HC Chen, JH Lee, YS Lin, HH Liou, PF Liu, LP Ger^*, KW Tsai^*. (2016) Aberrant DNA hypomethylation of miR-196b gene contributes to migration and invasion of oral cancer. Oncology Letters 11(6):4013-4021. (IF: 2.2, 216/326, ONCOLOGY)

2015

64.  PF Liu^#, JS Cheng^#, CL Sy^#, WC Huang, HC Yang, RL. Gallo, CM Huang, CW Shu^* (2015) IsaB Inhibits Autophagic flux to promote host transmission of methicillin-resistant Staphylococcus aureus. Journal of Investigative Dermatology 135(11):2714-2722. (IF: 5.7, 7/96 (<10%), DERMATOLOGY).

65.  PF Liu, YD Hsieh, YC Lin, A Two, CW Shu^*, CM Huang^* (2015) Propionibacterium acnes in the pathogenesis and immunotherapy of acne vulgaris. Current Drug Metabolism 16(4):245-254. (IF: 1.8, 244/352, PHARMACOLOGY & PHARMACY)

66.  WZ Liang^#, PF Liu^# (co-first author), E Fu, HS Chung, CR Jan, CH Wu, CW Shu^*, YD Hsieh^* (2015) Selective cytotoxic effects of low-power laser irradiation on human oral cancer cells. Lasers in Surgery and Medicine 47(9):756-764. (IF: 1.9, 119/312, SURGERY)

67.  IF Huang^#, IC Lin^#, PF Liu (co-first author), YC Liu, YD Hsieh, JJ Chen, CL Chen, HW Chang, CW Shu^* (2015) Lactobacillus acidophilus attenuates Salmonella-induced intestinal inflammation via TGF-β signaling. BMC Microbiology 15:203. (IF: 4.2, 46/163, MICROBIOLOGY)

2014

68.  PF Liu^#, CM Leung^#, YH Chang, JS Cheng, JJ Chen, CJ Weng, KW Tsai, CJ Hsu, YC Liu, PC Hsu, HW Pan^*, CW Shu^* (2014) ATG4B promotes colorectal cancer growth independent of autophagic flux. Autophagy 10(8):1454-1465. (IF: 14.3, 16/204(<10%), CELL BIOLOGY)

2013

69.  PF Liu, IF Huang, CW Shu^*, CM Huang^* (2013) Halitosis vaccines targeting FomA, a biofilm-bridging protein in Fusobacteria nucleatum. Current Molecular Medicine 13(8):1358-1367. (IF: 2.5, 102/195, MEDICINE, RESEARCH & EXPERIMENTAL)

70.  WS Chen, TW Chen, TH Yang, LY Hu, HW Pan, CM Leung, SC Li, MR Ho, CW Shu, PF Liu, SY Yu, YT Tu, WC Lin, TT Wu^*, KW Tsai^* (2013) Co-modulated behavior and effects of differentially expressed miRNA in colorectal cancer. BMC Genomics 14 (Suppl 5):S12. (IF: 3.7, 51/191, GENETICS & HEREDITY)

2012

71.  CW Shu^*, PF Liu, CM Huang^* (2012) High-throughput screening for drug discovery of autophagy

modulators. Combinatorial Chemistry & High Throughput Screening 15(9):721-729. (IF: 1.7, 49/75, CHEMISTRY, APPLIED)

2011

72.  PF Liu, T Nakatsuji, W Zhu, RL Gallo, CM Huang^* (2011) Passive immunoprotection targeting a secreted CAMP factor of Propionibacterium acnes as a novel immunotherapeutic for acne vulgaris. Vaccine 29(17):3230-8. (IF: 3.5, 68/195, MEDICINE, RESEARCH & EXPERIMENTAL)

2010

73.  PF Liu, WY Shi, WH Zhu, JW Smith, SL Hsieh, RL Gallo, CM Huang^* (2010) Vaccination targeting surface FomA of Fusobacterium nucleatum against bacterial co-aggregation: implication for treatment of periodontal infection and halitosis. Vaccine 28(19), 3496-3505. (IF: 3.5, 68/195, MEDICINE, RESEARCH & EXPERIMENTAL)

74.  CH Chen, XQ Zhang, CW Lo, PF Liu, YT Liu, RL Gallo, MF Hsieh^*, RT Schooley^*, CM Huang^* (2010) The essentiality of alpha-2-macroglobulin in human salivary innate immunity against new H1N1 swine origin influenza a virus. Proteomics 10(12), 2396-2401. (IF: 3.9, 18/86, BIOCHEMICAL RESEARCH METHODS)

75.  YK Wang, WC Chang, PF Liu, MK Hsiao, CT Lin, SM Lin, RL Pan^* (2010) Ovate family protein 1 as a plant Ku70 Interacting protein involving in DNA double-strand break repair. Plant Molecular Biology 74(4-5), 453-466. (IF: 3.8, 52/273(<20%), PLANT SCIENCES)

2009

76.  PF Liu, WH Zhu, CM Huang^* (2009) Vaccines and photodynamic therapies for oral microbial-related diseases. Current Drug Metabolism 10(1), 90-94. (IF: 1.8, 244/352, PHARMACOLOGY & PHARMACY) 

77.  PF Liu, SK Haake, RL. Gallo, CM Huang^* (2009) A novel vaccine targeting Fusobacterium nucleatum against abscesses and halitosis. Vaccine 27(10), 1589-1595. (IF: 3.5, 68/195, MEDICINE, RESEARCH & EXPERIMENTAL)

78.  PF Liu, CW Lo, CH Chen, MF Hsien, CM Huang^* (2009) Use of nanoparticles as therapy for methicillin-resistant Staphylococcus aureus infections. Current Drug Metabolism 10 (8), 875-884. (IF: 1.8, 244/352, PHARMACOLOGY & PHARMACY)

79.  SH Hsu, YY Hsiao, PF Liu, SM Lin, YY Luo, RL Pan^* (2009) Purification, characterization, and spectral analyses of histidine-tagged vacuolar H+-pyrophosphatase expressed in yeast. Botanical Studies 50, 291-301. (IF: 3.1, 76/273, PLANT SCIENCES)

2008

80.  PF Liu, YK Wang, WC Chang, HY Chang, RL Pan^* (2008) Regulation of Arabidopsis thaliana Ku genes at different developmental stages under heat stress. Biochimica et Biophysica Acta- Gene Regulatory Mechanisms 1779 (6-7), 402-407. (IF: 3.1, 23/79, BIOPHYSICS)

81.  PF Liu, WC Chang, YK Wang, HY Chang, RL Pan^* (2008) Signaling pathways mediating the suppression of Arabidopsis thaliana Ku gene expression by abscisic acid. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms 1779(3), 164-174. (IF: 3.1, 23/79, BIOPHYSICS)

82.   JY Fang, PF Liu, CM Huang^* (2008) Decreasing systemic toxicity via transdermal delivery of anticancer drugs. Current Drug Metabolism 9(7), 592-597. (IF: 1.8, 244/352, PHARMACOLOGY & PHARMACY)

83.  CW Shu, FC Sun, JH Cho, CC Lin, PF Liu, PY Chen, MDT Chang, HW Fu, YK Lai^* (2008) GRP78 and Raf-1 cooperatively confer resistance to endoplasmic reticulum stress-induced apoptosis. Journal of Cellular Physiology 215(3):627-35. (IF: 4.0, 14/87(<20%), PHYSIOLOGY)  

84.  WC Chang^#, YK Wang^#, PF Liu, YF Tsai, LR Kong, CK Lin, CH Yang, RL Pan^* (2008) Regulation of Ku gene promoters in Arabidopsis by hormones and stress. Functional Plant Biology 35(4):265-280. (IF: 2.7, 87/273, PLANT SCIENCE)

2007

85.  PF Liu, WC Chang, YK Wang, SB Munisamy, SH Hsu, HY Chang, SH Wu, RL Pan^* (2007) Differential regulation of Ku gene expression in etiolated mung bean hypocotyls by auxins. Biochimica et Biophysica Acta- Gene Regulatory Mechanisms 1769(7-8), 443-454. (IF: 3.1, 23/79, BIOPHYSICS) 

86.  YY Hsiao, YJ Pan, SH Hsu, YT Huang, TH Liu, CH Lee, CH Lee, PF Liu, WC Chang, YK Wang, LF Chien, RL Pan^* (2007) Functional roles of arginine residues in mung bean vacuolar H+-pyrophosphatase. Biochimica et Biophysica Acta- Bioenergetics 1767(7):965-73. (IF: 2.7, 34/79, BIOPHYSICS)

2005

87.  SY Kuo, LF Chien, RC Van, KH Yan, PF Liu, WC Chang, JK Wang, RL Pan^* (2005) Purification and subunit determination of H+-pyrophosphatase from endoplasmic reticulum-enriched vesicles of mung bean seedlings. Plant Science 169(5), 847-853. (IF: 4.1, 45/273 (<20%), PLANT SCIENCES)

88.  SY Kuo, LF Chien, YY Hsiao, RC Van, KH Yan, PF Liu, SJ Mao, RL Pan^* (2005) Proton pumping inorganic pyrophosphatase of endoplasmic reticulum-enriched vesicles from etiolated mung bean seedlings. Journal of Plant Physiology 162(2):129-38. (IF: 4.1, 45/273(<20%), PLANT SCIENCES)

2004

89.  KH Yan, PF Liu, HT Tzeng, WC Chang, WG Chou, RL Pan^* (2004) Characterization of DNA end-binding activities in higher plants. Plant Physiology and Biochemistry 42(7-8):617-22. (IF: 5.7, 24/273(<10%), PLANT SCIENCES) 

update-20251231