Associate Professor Cheng, Chih-Mei
E-mail:chmech@kmu.edu.tw
Education:
PhD, Kaohsiung Medical University , R.O.C.
Courses Offered:
Cell Culture and Tissue Engineering, Laboratory of Cell Culture and Tiassue Engineering
Specialty:
Biochemistry, Cell Biology, Molecular Biology
Academic Interests:
Mechanisms involved in GERD associated asthma
Mechanisms involved in enviromental disrupting chmical and allergic asthma
Publications:

  1. Tseng CH, Cheng CM, Tzeng CC, Peng SI, Yang CL, Chen YL*.Synthesis and anti-inflammatory evaluations of β-lapachone derivatives . Bioorganic & Medicinal Chemistry 21 (2013) 523–531

  2. Tseng CH, Chen YL, Hsu CY, Chen TC, Cheng CM, Tso HC, Lu YJ, Tzeng CC.* Synthesis and antiproliferative evaluation of 3-phenylquinolinylchalcone derivatives against non-small cell lung cancers and breast cancers .European Journal of Medicinal Chemistry 59 (2013) 274e282

  3. Tseng, C.-H., Chen, Y.-L., Hsu, C.-Y., Chen, T.-C., Cheng, C.-M., Tso, H.-C., Lu, Y.-J., and Tzeng, C.-C (2012, --). Synthesis and antiproliferative evaluation of 3-phenylquinolinylchalcone derivatives against non-small cell lung cancers and breast cancers. European Journal of Medicinal Chemistry. European Journal of Medicinal Chemistry, Accepted. (SCI). Nov 24;59C:274-282.

  4. Tseng CH, Tzeng CC, Chung KY, Kao CL, Hsu CY, Cheng CM, Huang KS, Chen YL Synthesis and antiproliferative evaluation of 6-aryl-11-iminoindeno[1,2-c]quinoline derivatives Bioorganic & Medicinal Chemistry. 2011.19: 7653–7663

  5. Tseng CH, Chen YL, Chung KY, Wang CH, Peng SI, Cheng CM, Tzeng CC Synthesis and antiproliferative evaluation of 2,3-diarylquinoline Derivatives Organic & Biomolecular Chemistry.2011. 9:3205

  6. Chiu HY, Chen CW, Lin HT, Hsieh CC, Lin SS, Cheng CM Study of gastric fluid induced cytokine and chemokine expression in airway smooth muscle cells and airway remodeling Cytokine. 2011.56:726-731

  7. Chih-Hua Tseng, Yeh-Long Chen, Sheng-Huei Yang, Peng Shin-I, Chih-Mei Cheng, Chein-Hwa Han, Shinne-Ren Lin, Cherng-Chyi Tzeng Synthesis and antiproliferative evaluation of certain iminonaphtho[2,3-b]furan Derivatives , Bioorganic & Medicinal Chemistry 18 (2010) 5172–5182 ( SCI) 
  8. Shih, PK, Chen, YC, Huang,YC Yu-Tang Chang,YT, Jian-Xun, Chen,JX, Cheng,CM*, Vitamin D3 ameliorates lung and muscle injury induced by reperfusion of bilateral femoral vessels in a rat model, 2010,Journal of Surgical Research, in press
  9. Chih Mei Cheng, CM, Hsieh,CC Chang Sheng Lin,CS, Dai,ZK Shih, PK, Everett, ML ,Thomas, AD, Parker, W Davis, RD, Lin,SS , Macrophage activation by gastric fluid suggests MMP involvement in aspiration-induced lung disease, Immunobiology 215 (2010) 173–181 (SCI) 
  10. Tseng CH , Chen YL, Chun KY, Cheng CM*, Wang CH ,Tzeng CC, Synthesis and antiproliferative evaluation of 6-arylindeno[1,2-c]quinolinederivatives, Bioorganic & Medicinal Chemistry (2009) : 7465–7476( SCI) 
  11. Tseng CC , CH, Lin CS, Shih PK, Tsao LT, Wang JP, Cheng CM,*, Tzeng CC, Chen YL,* Furo[30,20:3,4]naphtho[1,2-d]imidazole derivatives as potential inhibitors of inflammatory factors in sepsis, Bioorganic & Medicinal Chemistry 17 (2009) 6773–6779, (SCI) 
  12. Lee, Y.-H., Cheng, C.-M., Chang, Y.-F., Wang, T.-Y., and Yuo, C.-Y.* 2007. Apoptin T108 phosphorylation is not required for its tumor-specific nuclear localization but partially affects its apoptotic activity. Biochem. Biophys. Res. Commun. 354(2):391-5 (SCI) 
  13. Chang YF., Cheng ,C-M., Li-Kwan Chang., Jong YJ, You CY, 2006, The F-box protein Fbxo7 interacts with human inhibitor of apoptosis protein cIAP1 and promotes cIAP1 ubiquitination Biochem. Biophys. Res. Commun. 342 1022–1026( SCI) 

研討會論文
Cheng, C.-M, Chen, D.-Y, Lin, Y.-M., Yuo, C.-Y. 1999. Cloning and characterization of the Apoptin-associated proteins. The 14th Joint Ann. Conf. Biomed. Sci., Taipei, Taiwan.
Cheng, C.-M, Lien, W.-H., Lee, S.-Y., and Yuo, C.-Y. 2000. APAP1, an apoptin-associated protein, causes cell death. The 15th Joint Ann. Conf. Biomed. SCI., Taipei, Taiwan.
Cheng, C.-M., Chung, W.-Y., and Yuo, C.-Y. 2003. Apoptin induces apoptosis probably through the death effector domain-mediated pathway. The 11th Symposium on Recent Advances in Cellular and Molecular Biology, Kenting, Taiwan.
Cheng, C-M1., Chien, MS., Chen SY., Lee SJ., Yuo CY., 2005, Study and characterization of APAP1/DEDAF in zebrafish developmentThe 13th Symposium on Recent Advances in Cellular and Molecular Biology, Kenting, Taiwan.
An anti-inflammatory study of Ovatodiolide in Raw264.7 cells , Chen Y J, Hsieh C C,
Chen Y L, Cheng C-M, 2007,高雄醫學大學生命科學院 第一屆論文競試
Hsieh, C C ., Lin, CS., Cheng,C-M., Pro-Inflammatory Study of Gastric Fluid Acid in Raw 264.7 cells , 2007, 47th Annual meeting of American Society for Cell Biology
Chiu, HY, Cheng, CW, Lin, CS , Hsieh, CC, Lin,SS, Parker,W, Cheng, CM, 2009, Studies of Gastric Fluid in Rat Airway Smooth Muscle Cells, 97年度彰高輔合作研究成果發表會
Lee,SM, Ching T, Schneider,F, Holzknecht,Z ,Thomas,A Su,KY, Parker,W Davis,RD, Cheng,CM ,. Lin.SS, The Role of Macrophages in the Response to Aspirated Gastric Fluid in Lung Allografts , American J of Transplantation 9: 393-393 Suppl. 2 , 2009, Transplantation , IF 6.5, 1/21
Synthesis and Anti-inflammatory Evaluation of Furo[3’,2’:3,4]naphtho[1,2-d]imidazole Derivatives Shin-I Peng, Chih-Hua Tseng, Chang-Sheng Lin, Pin-Keng Shih, Chih-Mei Cheng, Yeh-Long Chen and Cherng-Chyi Tzeng 2010,高雄醫學大學生命科學院論文競試

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