Professor Chang, Hsueh-Wei

Dean, College of Life Science

E-mail: changhw@kmu.edu.tw   Tel: 2691

Education:

Ph.D. Department of Life Science, National Tsing-Hua University

Postdoctorial researcher, Johns Hopkins University School of Medicine, USA

Courses Offered:

Biochemisrty, Biology, Molecular Biology, Bioinformatics, Genomics, Special topic in cell biology, Special topic in Bioinformatics

Specialty:

Anticancer drug screening from natural product, SNP, Genomics, Cancer genetics, Bioinformatics, molecular avian gender identification.

Academic Honors:

[Technical Editor] 1. Theriogenology Insight -International journal of Reproduction in all Animals

[Guest editor for special issue] 1. The World Scientific Journal- Biochemistry domain 

[Editorial Board] 1. Recent Patents on Biomarkers; 2. The Open Systems Biology Journal; 3. The Open Access Journal of Science and Technology

Academic Interests:

1. Establishment of DNA damage or repair analytic platform for natural and synthetic drugs

Coperating with Institute of Natural Products to screen drugs with anti-cancer and antioxidative stress proterties.

2. Developing and renew of bioinformatics tool

Cooperation with computational experts to improve the bioinformatics tool related to SNP genotyping, SNP-SNP interaction, feature selection

3. SNP genotyping, haplotyping and association study

DNA from any source, e.g., hair shafts, blood, or buccal, urine and saliva is suitable for analysis. Under properly sampling for certain diseases, the risk factor for specific SNP associated with diseases is estimated. Mining haplotype-based SNP candidates is concerned. Recently topics include osteoporosis, bladder and oral cancers.

4. Molecular gender identification of birds

High throughput analysis for gender identification of birds. 

5. Development of noninvasive DNA extraction from patients.

Currently, we are successfully performed PCR from urine and saliva extracted DNA.

 

image Publications :

  1. Yin-Chang Liu*, Hsueh-Wei Chang, Yi-Chyi Lai, Sheue-Ting Ding, Jih-Lin Ho. Serum responsiveness of the rat PCNA promoter involves the proximal ATF and AP-1 sites. FEBS Lett 441(2):200-204. (1998) [SCI]
  2. Bor-Show Tzang, Yi-Chyi Lai, Mandy Hsu, Hsueh-Wei Chang, Chia-Chin Chang, Pien C. Huang, Yin-Chang Liu*. Function and sequence analyses of tumor suppressor gene p53 of CHO.K1 cells. DNA Cell Biol 18(4):315-321. (1999)[SCI]
  3. Hsueh-Wei Chang, Yi-Chyi Lai, Ching-Yang Cheng, Jih-Lin Ho, Sheue-Ting Ding, Yin-Chang Liu*. UV inducibility of rat proliferating cell nuclear antigen gene promoter. J Cell Biochem 73(3):423-432. (1999) [SCI]
  4. Yu-Ching Chang, Hsueh-Wei Chang, Chu-Bin Liao, Yin-Chang Liu*. The role of p53, DNA repair and oxidative stress in UVC induction of PCNA expression. Annals N Y Acad Sci 973:384-391. (2002) [SCI]
  5. Gad Singer, Robert J. Kurman, Hsueh-Wei Chang, Sarah K. R. Cho, Ie-Ming Shih*. Diverse tumorigenic pathways in ovarian serous carcinoma. Am J Pathology 160(4):1223-1228. (2002) [SCI]
  6. Hsueh-Wei Chang, Ching-Yui Yen, Shyun-Yui Liu, Gad Singer, Ie-Ming Shih*. Genotyping analysis using human hair shaft. Cancer Epidemiology Biomarkers & Prevention 11(9):925-929. (2002) [SCI]
  7. Hsueh-Wei Chang, Syed Ali, Robert J. Kurman, Ie-Ming Shih*. Detection of Allelic imbalance in ascitic supernatant by digital single nucleotide polymorphism analysis. Clinical Cancer Research 8(8):2580-2585. (2002) [SCI]
  8. Hsueh-Wei Chang, Shing M. Lee, Steven N. Goodman, Gad Singer, Sarah K. R. Cho, Lori J. Sokoll, Fredrick J. Montz, Richard Roden, Zhen Zhang, Daniel W. Chan, Robert J. Kurman, Ie-Ming Shih*. Assessment of plasma DNA levels, allelic imbalance and CA-125 as diagnostic tests for cancer. J Natl Cancer Institute 94(22):1697-1703. (2002) [SCI]
  9. Hsueh-Wei Chang, Cheng-Hong Yang, Phei-Lang Chang, Yu-Huei Cheng, and Li-Yeh Chuang*.SNP-RFLPing: restriction enzyme mining for SNP in genomes. BMC Genomics 7:30. (2006) [SCI]
  10. Hung-Fu Tseng*, Chen-Kang Chang, Hsiu-Fen Tan, Shu-Er Yang, Hsueh-Wei Chang. Seroepidemiology study of rubella antibodies among pregnant women from seven Asian countries: evaluation of the rubella vaccination program in Taiwan. Vaccine. Vaccine 24(29-30):5772-5777. (2006) [SCI]
  11. Li-Yeh Chuang, Cheng-Hong Yang, Yu-Huei Cheng, De-LeungGu, Phei-Lang Chang, Ke-Hung Tsui, and Hsueh-Wei Chang*V-MitoSNP: visualization of human mitochondrial SNPs. BMC Bioinformatics7:379 (2006) [SCI]
  12. Gau-Tyan Lin*, Hsueh-Wei Chang, Chih-Shan Liu, Peng-Ju Huang, Hsien-Chung Wang, Yuh-Min Cheng. De novo 617G-A nucleotide mutation of ACVR1 gene in Taiwanese patient with fibrodysplasia ossificans progressiva. Journal of Human Genetics51(12):1083-1086. (2006) [SCI]
  13. 周以正, 鍾郁涵, 張學偉, 蔡奇立, 郭金泉. 論台灣鮭魚身世之謎和正名.自然保育季刊56:51-58. Dec. (2006)
  14. Ritu Salani, Ilana Beuberger, Robert Kurman, Robert Bristow, Hsueh-Wei Chang, Tian-Li Wang, Ie-Ming Shih*. Expression of extracellular matrix proteins in ovarian serous tumors. International Journal of Gynecological Pathology 26(2):141-146. Apr. (2007)[SCI]
  15. Cheng-Wen Lin*, Ping-Feng Tu, Nai-Wan Hsiao, Ching-Yao Chang, Lei Wan, Yu-Tsun Lin, Hsueh-Wei Chang. Identification of a novel septin 4 protein binding to human herpesvirus 8 kaposin A protein using a phage display cDNA library. Journal of Virological Methods143(1): 65-72. Jul. (2007) [SCI]
  16. Li-Yeh Chuang, Cheng-Hong Yang*, Yu-Huei Cheng, Hsueh-Wei Chang. A mixed method for proving exact SNP IDs from sequences. Biomedical Engineering: Applications, Basis and Communications 19(4): 251-257. Aug. (2007) [EI]
  17. Tsai-Ming Lin†, Hsueh-Wei Chang†(†equal contribution), Kei-Hung Wang, An-Pei Kao, Chia-Cheng Chang, Chung-Sheng Lai, Cheng-Hao Wen, and Sin-Dan Lin*. Isolation and identification of mesenchymal stem cells from human lipoma tissue. Biochemical and Biophysical Research Communications 361(4): 883-889. Oct. (2007) [SCI]
  18. Chien-Te Lin, Hsueh-Wei Chang, Gow-Shing Chen*, Chi-Ling Lin, De-Leung Gu. Herpes Simplex Mimicking Herpes Zoster in a 3-year-old Child- A Case Report. Dermatologica Sinica 25(3):194-199. Oct. (2007)
  19. Hsueh-Wei Chang, Yu-Huei Cheng, Tai-Chen Chen, Cheng-San Yang, Li-Yeh Chuang, and Cheng-Hong Yang*. A novel method providing exact SNP IDs from sequences. IAENG International Journal of Computer Science, 34:1, IJCS_34_1_17. Aug. (2007)
  20. Hsueh-Wei Chang*, Ke-Hung Tsui, Li-Chun Shen, Hurng-Wern Huang, Shen-Nien Wang, Phei-Lang Chang*. Urinary cell-free DNA as a potential tumor marker in bladder cancer. International Journal of Biological Markers 22(4):287-294. Dec. (2007) [SCI]
  21. Ching-Shen Liu, Thau-Ming Cham, Cheng-Hong Yang, Hsueh-Wei Chang, Chia-Hong Chen and Li-Yeh Chuang*. Antibacterial properties of Chinese herbal medicines against nosocomial antibiotic resistant strains of Pseudomonas aeruginosa in Taiwan. American Journal of Chinese Medicine35(6):1047-1060. Dec. (2007)[SCI]
  22. Li-Yeh Chuang, Hsueh-Wei Chang, Chung-Jui Tu, and Cheng-Hong Yang. Improved binary PSO for feature selection using gene expression data. Computational Biology and Chemistry 32:29-37. Feb. (2008)[SCI]
  23. Hsueh-Wei Chang*, Chun-An Cheng, De-Leung Gu, Cheng-Hao Wen, Chia-Che Chang, Yii-Cheng Chou, Cheng-Te Yao, Chi-Li Tsai, Ta-Ching Chou, Chien-Chung Cheng*. High-throughput avian molecular sexing by SYBR green-based real-time PCR combined with melting curve analysis. BMC Biotechnology 8:12 Feb. (2008)[SCI]
  24. Gau-Tyan Lin, Hung-Fu Tseng, Chen-Kang Chang, Li-Yeh Chuang, Cheng-Hong Yang, Chung-Jui Tu, Chih-Shan Liu, Eng-Chi Wang, Hsiu-Fen Tan, Chia-Che Chang, Cheng-Hao Wen, Hsiang-Chi Chen, Hsueh-Wei Chang*. SNP combinations in chromosome-wide genes are associated with bone mineral density in Taiwanese women. Chinese Journal of Physiology91(1):32-41 Feb. (2008) [SCI]
  25. Hsueh-Wei Chang, Li-Yeh Chuang, Chang-Hsuan Ho, Phei-Lang Chang and Cheng-Hong Yang*. Odds ratio-based genetic algorithms for generating SNP barcodes of genotypes to predict disease susceptibility. OMICS: A Journal of Integrative Biology 12(1):71-81 Mar. (2008) [SCI]
  26. Ching-Yu Yen, Shyun-Yui Liu, Chung-Ho Chen, Hung-Fu Tseng, Li-Yeh Chuang, Cheng-Hong Yang, Ying-Chu Lin, Cheng-Hao Wen, Chang-Hsuan Ho, Hsiang-Chi Chen, Shaio-Ting Wang, Cheng-Wen Lin, Hsueh-Wei Chang*. Combinational polymorphisms of four DNA repair genes XRCC1, XRCC2, XRCC3 and XRCC4 and their association with oral cancer in Taiwan. Journal of Oral Pathology & Medicine 37(5): 271-277 May. (2008) [SCI]
  27. Hsueh-Wei Chang*, Ta-Ching Chou, De-Leung Gu, Chun-An Cheng, Chia-Che Chang, Cheng-Te Yao, Li-Yeh Chuang, Cheng-Hao Wen, Yii-Cheng Chou, Kock-Yee Tan, Chien-Chung Cheng. An improved PCR method for molecular gender identification of eagle. Molecular and Cellular Probes 22(3): 184-188 Jun. (2008) [SCI]
  28. Hsueh-Wei Chang*, De-Leung Gu, San-Hua Su, Chia-Che Chang, Chun-An Cheng, Hurng-Wern Huang, Cheng-Te Yao, Ta-Ching Chou, Li-Yeh Chuang, Chien-Chung Cheng*. High-throughput gender identification of Accipitridae eagles with real-time PCR using TaqMan probes. Theriogenology70:83-90 (2008) [SCI]
  29. Li-Yeh Chuang, Cheng-Hong Yang, Ke-Hung Tsui, Yu-Huei Cheng, Phei-Lang Chang, Cheng-Hao Wen, and Hsueh-Wei Chang*. Restriction enzyme mining for SNPs in genomes. Anticancer Research28(4A):2001-2007. Review. Jul-Aug. (2008) [SCI]
  30. Ming-Tsai Liang, Cheng-Hong Yang*, Shun-Tai Li, Cheng-San Yang, Hsueh-Wei Chang, Ching-Shen Liu, Thau-Ming Cham, and Li-Yeh Chuang*. Antibacterial and antioxidant properties of Ramulus Cinnamomi using supercritical CO2 extraction. European Food Research and Technology 227 (5):1387-1396. Sept. (2008) [SCI]
  31. Cheng-Hong Yang, Li-Yeh Chuang* Yu-Huei Cheng, Cheng-Hao Wen, Phei-Lang Chang, and Hsueh-Wei Chang*. SNP ID-info: SNP ID searching and visualization platform. OMICS: A Journal of Integrative Biology 12(3): 217-226. Sept. (2008) [SCI]
  32. Cheng-Hong Yang, Yu-Huei Cheng, Li-Yeh Chuang*, and Hsueh-Wei Chang. SNP-Flankplus: SNP ID-centric retrieval for SNP flanking sequences. Bioinformation 3(4), 147-149 Dec. (2008) (Cited in PubMed)
  33. Hsueh-Wei Chang, Cheng-Hong Yang*, Chang-Hsuan Ho, Cheng-Hao Wen, and Li-Yeh Chuang*. Generating SNP barcode to evaluate SNP-SNP interaction of disease by particle swarm optimization. Computational Biology and Chemistryshort communication. 33 (1):114-119. Feb. (2009) [SCI]
  34. Hsiu-Fen Tan, Chia-Yu Yeh, Hsueh-Wei Chang, Chen-Kang Chang and Hung-Fu Tseng*. Private doctors' practices, knowledge, and attitude to reporting of communicable diseases: A national survey in Taiwan. BMC Infectious Diseases 9:11 Jan. (2009) [SCI]
  35. Cheng-Hong Yang, Tsung-Mu Shih, Yu-Chen Hung, Hsueh-Wei Chang*, and Li-Yeh Chuang. Extract-SAGE: An integrated platform for cross-analysis and GA-based selection of SAGE data. Bioinformation 3(7):291-292. Feb. (2009) (Cited in PubMed)
  36. Hsueh-Wei Chang§, Jing-Iong Yang§, Hsiao-Yun Huang, Jin-Chywan Gwo, Ying-Fang Su, Cheng-Hao Wen, Yii-Cheng Chou*. A novel growth hormone 1 gene-derived probe for Oncorhynchus masou formosanum distinguished from the Oncorhynchus subspecies. Molecular and Cellular Probes 23:103-106. Apr. (2009) [SCI]
  37. Li-Yeh Chuang, Chao-Hsuan Ke, Hsueh-Wei Chang, and Cheng-Hong Yang*. A two stage feature selection methods for gene expression data. OMICS: A Journal of Integrative Biology 13(2):127-137. Apr. (2009) [SCI]
  38. Gau-Tyan Lin, Hung-Fu Tseng, Cheng-Hong Yang, Ming-Feng Hou, Li-Yeh Chuang, Hsiao-Ting Tai, Ming-Hong Tai*, Yu-Huei Cheng, Cheng-Hao Wen, Chih-Shan Liu, Chih-Jen Huang, Chun-Lin Wang, and Hsueh-Wei Chang*. Combinational polymorphisms of seven CXCL12-related genes are protective against breast cancer in Taiwan. OMICS: A Journal of Integrative Biology 13(2): 165-172. Apr. (2009) [SCI]
  39. Hsueh-Wei Chang, Li-Yeh Chuang*, Yu-Huei Cheng, Yu-Chen Hung, Cheng-Hao Wen, De-Leung Gu, and Cheng-Hong Yang*. Prim-SNPing: a primer designer for cost-effective SNP genotyping. Biotechniques 46(6):421-431. May. (2009) [SCI]
  40. Cheng-Hong Yang, Li-Yeh Chuang, Yu-Huei Cheng, Cheng-Hao Wen, and Hsueh-Wei Chang*. Dynamic programming for SNP ID identification in systematic association studies. Kaohsiung Journal of Medical Sciences 25(04):165-176. Jul. (2009) [SCI]
  41. Hsueh-Wei Chang, Li-Yeh Chuang*, Yan-Jhu Chang, Yu-Huei Cheng, Yu-Chen Hung, Hsiang-Chi Chen, and Cheng-Hong Yang*. LD2SNPing: Linkage disequilibrium plotter and RFLP enzyme mining for tag SNPs. BMC Genetics 10: 26 Jun. (2009) [SCI]
  42. Ching-Yu Yen, Shyun-Yui Liu, Chao-Hsiang Chang, Chung-Ho Chen*, Hung-Fu Tseng, De-Leung Gu, Li-Yeh Chuang, Cheng-Hao Wen, Hsueh-Wei Chang*. MMP1 and MMP10 but not MMP12 are the potential oral cancer markers. Biomarkers. 14(4):244-249. Jun. (2009) [SCI]
  43. Hsueh-Wei Chang, Li-Yeh Chuang*, Yu-Huei Cheng, Chang-Hsuan Ho, Cheng-Hao Wen, and Cheng-Hong Yang*. Seq-SNPing: multiple-alignment tool for SNP discovery, SNP ID identification and RFLP genotyping. OMICS: A Journal of Integrative Biology 13(3):253-260. Jun. (2009) [SCI]
  44. Cheng-Hong Yang, Yu-Huei Cheng, Li-Yeh Chuang*, Hsueh-Wei Chang. Specific PCR product primer design using memetic algorithm. Biotechnology Progress 25(3):745-53 May-Jun. (2009) [SCI]
  45. Cheng-Hong Yang, Hsueh-Wei Chang*, Yu-Huei Cheng, and Li-Yeh Chuang*. Novel generating protective SNP barcode for breast cancer using particle swarm optimization. Demiology33(2):147-154.Aug. (2009)[SCI]
  46. Chung-Yi Chen, Pei-Yu Wu, Tsi-Shu Huang, Chen-Wu Lin, Yi-Chi Li, Ruey-Hwang Chou, Hsueh-Wei Chang, and Hui-Min Wang*. The sour taste-modifying protein (Miraculin), tyrosinase inhibitors and antioxidants from Synsepalum dulcificum. Current Nutrition & Food Science 5(3):172-179. Aug. (2009)
  47. Chien-Chih Chiu§Hsueh-Wei Chang§ (§ equal contribution), Da-Wei Chuang, Fang-Rong Chang, Yu-Ching Chang, Yu-Shan Cheng, Ming-Tz Tsai, Wan-Yu Chen, Su-Shuo Lee, Chih-Kuang Wang, Jeff Yi-Fu Chen, Hui-Min Wang, Chao-Chieh Chen, Yin-Chang Liu*, Yang-Chang Wu*. Fern plant-derived protoapigenone leads to DNA damage, apoptosis and G2/M arrest in lung cancer cell line H1299. DNA and Cell Biology 28(10):501-506. Oct. (2009) [SCI]
  48. Ching-Yu Yen, Min-Chi Lu, Ching-Cherng Tzeng, Jia-Yan Huang, Hsueh-Wei Chang, Ruey-Shyang Chen, Shyun-Yeu Liu, Shih-Tung Liu, Biehuoy Shieh and Ching Li*. Detection of EBV infection and gene expression in oral cancer from patients in Taiwan by microarray analysis. Journal of Biomedicine and Biotechnology Article ID 904589:1-15. Dec. (2009) [SCI]
  49. Jyh-Ferng Yang, Cheng-Hong Yang, Hsueh-Wei Chang, Cheng-San Yang, Che-Wei Lin, and Li-Yeh Chuang*. Antioxidant and antibacterial properties of Pericarpium trichosanthis against nosocomial drug resistant strains of Acinetobacter baumannii in Taiwan. Journal of Medicinal Plants Research 3(11): 982-991. Nov. (2009) [SCI]
  50. Ta-Ching Chou, Cheng-Te Yao, San-Hua Su, Yu-Chen Hung, Wan-Shing Chen, Chien-Chung Cheng, Chao-Neng Tseng, Hui-Min Wang, Yii-Cheng Chou, Steven Shoei-Lung Li, De-Leung Gu, Hsueh-Wei Chang*. Validation of Spilornis cheela hoya TaqMan probes for potential gender identification of many Accipitridae speciesTheriogenology 73:404-411. Feb. (2010) [SCI]
  51. Cheng-Hong Yang, Li-Yeh Chuang*, Yu-Huei Cheng, De-Leung Gu, Chung-Ho Chen, Hsueh-Wei Chang*. Methyl-typing: An improved and visualized COBRA software for epigenomic studies. FEBS Letters 584:739-744. Feb. (2010) [SCI]
  52. Ching-Yu Yen, Chien-Chih Chiu, Fang-Rong Chang, Jeff Yi-Fu Chen, Chi-Ching Hwang, You-Cheng Hseu, Hsin-Ling Yang, Alan Yueh-Luen Lee, Ming-Tz Tsai, Zong-Lun Guo, Yu-Shan Cheng, Yin-Chang Liu, Yu-Hsuan Lan, Yu-Ching Chang, Ying-Chin Ko, Hsueh-Wei Chang*, Yang-Chang Wu*. 4β-Hydroxywithanolide E from Physalis peruviana (golden berry) inhibits growth of human lung cancer cells through DNA damage, apoptosis and G2/M arrest. BMC Cancer 10:46 Feb. (2010) [SCI]
  53. Hsueh-Wei Chang*, Yii-Cheng Chou, Ying-Fang Su, Chun-An Cheng, Cheng-Te Yao, Chi-Li Tsai,Hsien-Chung Lee, Chien-Chung Cheng*. Molecular phylogeny of the Pycnonotus sinensis and Pycnonotus taivanus in Taiwan based on sequence variations of nuclear CHD and mitochondrial cytochrome b genes. Biochemical Systematics and Ecology38:195-201. Apr.(2010) [SCI]
  54. Hsueh-Wei Chang, Yu-Huei Cheng, Li-Yeh Chuang*, and Cheng-Hong Yang*. SNP-RFLPing 2: an updated and integrated PCR-RFLP database tool for SNP genotyping. BMC Bioinformatics11:173 Apr. (2010) [SCI]
  55. Jeff Yi-Fu Chen, Chi-Ching Hwang, Wei-Yi Chen, Jing-Ching Lee, Tzu-Fun Fu, Kang Fang, Ying-Chieh Chu, Ya-Lan Huang, Jia-Cheng Lin, Wen-Hui Tsai, Hsueh-Wei Chang, Bing-Hung Chen*, Chien-Chih Chiu*. Additive effects of C2-ceramide on Paclitaxel-induced premature senescence of human lung cancer cells. Life Sciences 87(11-12):350-7. Sep. (2010) [SCI]
  56. Jyh-Ferng Yang, Cheng-Hong Yang, Hsueh-Wei Chang, Cheng-San Yang, Shao-Ming Wang, Ming-Che Hsieh, and Li-Yeh Chuang*. Chemical composition and antibacterial activities of Illicium verum against antibiotic-resistant pathogens. J Med Food 13(5):1254-1262. Oct. (2010[SCI]
  57. Cheng-Hong Yang, Li-Yeh Chuang*, Yu-Huei Cheng, Hsueh-Wei Chang*. Confronting two-pair primer design for enzyme-free SNP genotyping using a genetic algorithm.BMC Bioinformatics11:509. Oct. (2010) [SCI]
  58. Hui-Min Wang, Jian-Liang Pan, Chun-Yen Chen, Chien-Chich Chiu, Mu-Hoe Yang, Hsueh-Wei Chang, Jo-Shu Chang. Identification of anti-lung cancer extract from Chlorella vulgaris C-C by antioxidant property using supercritical carbon dioxide extraction. Process Biochemistry 45(12):1865-1872. Dec. (2010) [SCI]
  59. Hui-Min Wang, Kuo-Chen Cheng, Cheng-Jung Lin, Shu-Wei Hsu, Wei-Cheng Fang, Tai-Feng Hsu, Liang-Cheng Su, Chien-Chih Chiu, Hsueh-Wei Chang, Chun-Hua Hsu, Alan Yueh-Luen Lee*. Obtusilactone A and (-)-sesamin induce apoptosis in human lung cancer cells via inhibiting mitochondrial Lon protease and activating DNA damage checkpoints. Cancer Science 101(12):2612-2620, Dec. (2010) [SCI]
  60. Cheng-Hong Yang, Li-Yeh Chuang, Tsung-Mu Shih, and Hsueh-Wei Chang*. hSAGEing: An improved SAGE-based software for identification of human tissue-specific or common tumor markers and suppressors. PLoS One 5(12): e14369.(2010) [SCI]
  61. Hurng-Wern Huang, Ying-Fang Su, Cheng-Te Yao, Yu-Chen Hung, Chao-Chieh Chen, Chien-Chung Cheng*, Steven Shoei-Lung Li, Hsueh-Wei Chang*. High-throughput gender identification of three Columbidae species using melting curve analysisTheriogenology 75:73-79. Jan. (2011) [SCI]
  62. Hsin-Ling Yang, Yueh-Hsiung Kuo, Ching-Tsan Tsai, Yi-Ting Huang, Ssu-Ching Chen, Hsueh-Wei Chang, Elong Lin, Wen-Hsin Lin, You-Chen Hseu*. Anti-metastatic activities of Antrodia camphorata against human breast cancer cells mediated through suppression of the MAPK signaling pathway. Food and Chemical Toxicology49(1):290-298. Jan. (2011) [SCI]
  63. Bing-Hung Chen, Hsueh-Wei Chang, Hsuan-Min Huang, Inn-Wen Chong, Jia-Shing Chen, Chung-Yi Chen*, and Hui-Min Wang*. (-)–Anonaine induces oxidative stress and DNA damage to inhibit H1299 cell growth. Journal of Agricultural and Food Chemistry 59(6):2284-2290. Mar. (2011) [SCI]
  64. Cheng-Hong Yang, Hsueh-Wei Chang*, Chang-Hsuan Ho, Yii-Cheng Chou, and Li-Yeh Chuang*. Conserved PCR primer set designing for closely-related species to complete mitochondrial genome sequencing using a sliding window-based PSO algorithm. PLoS One 6(3):e17729. Mar. (2011) [SCI]
  65. Chien-Chih Chiu, Po-Len Liu, Kuang-Jing Huang, Hui-Min Wang, Kuo-Feng Chang, Chon-Kit Chou, Fang-Rong Chang, Inn-Wen Chong, Kang Fang, Jia-Shing Chen, Hsueh-Wei Chang*, Yang-Chang Wu*. Goniothalamin inhibits growth of human lung cancer cells through DNA damage, apoptosis and reduced migration ability. Journal of Agricultural and Food Chemistry59(8):4288-4293. May (2011) [SCI]
  66. You-Cheng Hseu, Chi-Rei Wu, Hsueh-Wei Chang, K.J. Senthil Kumar, Ming-Kuem Lin, Chih-Sheng Chen, Hsin-Ju Cho, Chun-Yin Huang, Chih-Yang Huang, Hong-Zin Lee, Wen-Tsong Hsieh, Jing-Gung Chung, Hui-Min Wang, and Hsin-Ling Yang*. Inhibitory effects of Physalis angulata on tumor metastasis and angiogenesis. Journal of Ethnopharmacology 135(3):762-771. Jun. (2011) [SCI]
  67. Sin-Daw Lin*, Shu-Hung Huang, Yun-Nan Lin, Sheng-Hua Wu, Hsueh-Wei Chang, Tsai-Ming Lin, Chee-Yin Chai, Chung-Sheng Lai. Engineering adipose tissue from uncultured human adipose stromal vascular fraction on gelatin sponge and collagen matrix scaffolds. Tissue Engineering, Part A. 17(11-12):1489-1498. Jun. (2011) [SCI].
  68. Cheng-Hong Yang, Li-Yeh Chuang*, Yu-Jung Chen, Hung-Fu Tseng, and Hsueh-Wei Chang*. Computational analysis for simulated SNP interactions between twenty-six growth factor-related genes in breast cancer association study. OMICS: A Journal of Integrative Biology 15(6):399-407. Jun. (2011) [SCI]
  69. James Cheng-Chung Wei, Jeng-Hsien Yen, Suh-Hang Hank Juo, Wei-Chiao Chen, Yu-Shiuan Wang, Yi-Ching Chiu, Tusty-Jiuan Hsieh, Yuh-Cherng Guo, Chun-Huang Huang, Ruey-Hong Wong, Hui-Po Wang, Ke-Li Tsai, Yang-Chang Wu, Hsueh-Wei Chang, Edward Hsi, Wei-Pin Chang, Wei-Chiao Chang*. Association of ORAI1 haplotypes with the risk of HLA-B27 positive ankylosing spondylitis. PLoS One 6(6): e20426. Jun. (2011) [SCI]
  70. Jing-Iong Yang*, Hsiao-Yun Huang, Yii-Cheng Chou, Chien-Cheng Chen, Guo-Chi Lee, Hsueh-Wei Chang*. Rapid and economic DNA extraction from a single salmon egg for real-time PCR amplification. Bioscience, Biotechnology, and Biochemistry 75(10): 2014-2017. Oct. (2011) [SCI]
  71. Huey-Er Lee, Chiung-Yu Li, Hsueh-Wei Chang, Yi-Hsin Yang, Ju-Hui Wu*. Effects of different denture cleaning methods to remove Candida albicans from acrylic resin denture based material. Journal of Dental Sciences 6(4):216-220. Dec. (2011) [SCI]
  72. Cheng-Hong Yang, Fang-Rong Chang, Hsueh-Wei Chang, Shao-Ming Wang, Ming-Che Hsieh, and Li-Yeh Chuang*. Investigation of the antioxidant activity of Illicium verum extracts. Journal of Medicinal Plants Research 6(2): 314-324. Jan. (2012)
  73. Elong Lin, Wen-Hsin Lin, Sheng-Yang Wang, Chih-Sheng Chen, Jiuun-Wang Liao, Hsueh-Wei Chang, Ssu-Ching Chen, Kai-Yuan Lin, Lai Wang, Hsin-Ling Yang*, You-Cheng Hseu*. Flavokawain B inhibits growth of human squamous carcinoma cells: Involvement of apoptosis and cell cycle dysregulation in vitro and in vivo. Journal of Nutritional Biochemistry 23(4):368-78. Apr. (2012) [SCI]
  74. Bing-Hung Chen*, Mei-Huei Hung, Jeff Yi-Fu Chen, Hsueh-Wei Chang, Meng-Lung Yu, Lei Wan, Fuu Jen Tsai, Tzu-Pin Wang, Tzu-Fun Fu, Chien-Chih Chiu*. Anti-allergic activity of grape seed extract (GSE) on RBL-2H3 mast cells. Food Chemistry 132(2):968-974. May (2012) [SCI]
  75. Li-Yeh Chuang, Yu-Da Lin, Hsueh-Wei Chang*, and Cheng-Hong Yang*. An improved PSO algorithm for generating protective SNP barcodes in breast cancer. PLoS One 7(5): e37018May (2012) [SCI]
  76. Fang-Ming Chen§, Hsueh-Wei Chang§ (§equal contribution), Sheau-Fang Yang, Ya-Fang Huang, Pei-Yung Nien, Yao-Tsung Yeh*, Ming-Feng Hou*. The mitogen-activated protein kinase phosphatase-1 (MKP-1) gene is a potential methylation biomarker for malignancy of breast cancer. Experimental & Molecular Medicine 44(5):356-62. May (2012) [SCI]
  77. Chao-Chieh Chen, Yu-Shiuan Liu, Chien-Chung Cheng, Chun-Lin Wang, Ming-Hui Liao, Chao-Neng Tseng*, Hsueh-Wei Chang*. High-throughput gender identification by melting curve analysis in blue-breasted quail and chicken. Theriogenology77(9):1951-1958. Jun. (2012) [SCI]
  78. Li-Yeh Chuang, Hsueh-Wei Chang*, Ming-Cheng Lin, Cheng-Hong Yang*. Chaotic particle swarm optimization for detecting SNP-SNP interactions for CXCL12-related genes in breast cancer prevention. European Journal of Cancer Prevention 21(4):336-42. Jul. (2012) [SCI]
  79. Cheng-Hong Yang, Li-Yeh Chuang, Yu-Huei Cheng, Yu-Da Lin, Chun-Lin Wang, Cheng-Hao Wen, Hsueh-Wei Chang*. Single nucleotide polymorphism barcoding to evaluate oral cancer risk using odds ratios-based genetic algorithms. Kaohsiung Journal of Medical Sciences 28(7): 362-368. Jul. (2012) [SCI]
  80. Jing-Iong Yang, Chi-Chen Yeh, Jin-Ching Lee, Szu-Cheng Yi, Chao-Neng Tseng*, Hsueh-Wei Chang*. Aqueous extracts of the edible Gracilaria tenuistipitata are protective against H2O2-induced DNA damage. Molecules 17:7241-7254. Jun. (2012) [SCI]
  81. Li-Yeh Chuang, Hsueh-Wei Chang*, Jui-Hung Tsai, and Cheng-Hong Yang*. Features for computational operon prediction in procaryotes. Brief Functional Genomics 11(4): 291-299. Jul. (2012) [SCI]
  82. Jin-Bor Chen, Yi-Hsin Yang, Wen-Chin Lee, Chia-Wei Liou, Tsu-Kung Lin, Yueh-Hua Chung, Li-Yeh Chuang, Cheng-Hong Yang*, Hsueh-Wei Chang*. Sequence-based polymorphisms in the mitochondrial D-loop and potential SNP predictors for chronic dialysis. PLoS One 7(7): e41125Jul. (2012) [SCI]
  83. Li-Yeh Chuang, Ming-Cheng Lin, Hsueh-Wei Chang, and Cheng-Hong Yang*. Chaotic particle swarm optimization for prediction of SNP combinations associated with a low bone mineral density risk. Lecture Notes in Engineering and Computer Science, 1:111-116. Jul. (2012)
  84. Ching-Yu Yen, Chien-Chih Chiu, Rou-Wen Huang, Chi-Chen Yeh, Kuang-Jing Huang, Kuo-Feng Chang, You-Cheng Hseu, Fang-Rong Chang, Hsueh-Wei Chang*, Yang-Chang Wu*. Goniothalamin inhibits growth of oral cancer cells through apoptosis, DNA damage, and ROS induction. Mutation Research- Genetic Toxicology and Environmental Mutagenesis 747(2): 252-258. Sep. (2012) [SCI]
  85. Chao-Chieh Chen, Hui-Tzu Chiu, Yung-Ting Chang, Yii-Cheng Chou, Jie Lin, Chien-Chung Cheng, Ming-Huei Liao*, Hsueh-Wei Chang*. An improved methodology for gender identification of Pygoscelis papuaTheriogenology Insight 2(2):93-98. Sep. (2012)
  86. Hsueh-Wei Chang*, Li-Yeh Chuang*, Ming-Tz Tsai, and Cheng-Hong Yang*. The importance of integrating SNP and cheminformatics resources to pharmacogenomics. Current Drug Metabolism13(7):991-999. Sep. (2012) [SCI]
  87. Chi-Chen Yeh, Jing-Iong Yang, Jin-Ching Lee, Chao-Neng Tseng, Ya-Ching Chan, You-Cheng Hseu, Jen-Yang Tang, Li-Yeh Chuang, Hurng-Wern Huang, Fang-Rong Chang*, Hsueh-Wei Chang*. Anti-proliferative effect of methanolic extract of Gracilaria tenuistipitata on oral cancer cells involves apoptosis, DNA damage, and oxidative stress. BMC Complementary and Alternative Medicine12:142. Sep.(2012) [SCI]
  88. Chi-Chen Yeh, Chao-Neng Tseng, Jing-Iong Yang, Hurng-Wern Huang, Yi Fang, Jen-Yang Tang, Fang-Rong Chang*, Hsueh-Wei Chang*. Antiproliferation and induction of apoptosis by ethanolic extract of Gracilaria tenuistipitata on oral cancer cells. Molecules 17:10916-10927.Sep. (2012) [SCI]
  89. Yung-Fu Chang, Hui-Ju Chou, Ying-Cheng Yen, Hsueh-Wei Chang, Yi-Ren Hong, Hurng-Wern Huang*, and Chao-Neng Tseng*. Agrin induces association of Chrna1 mRNA and nicotinic acetylcholine receptor in C2C12 myotubes. FEBS Lett 586(19):3111-6 Sep. (2012) [SCI]
  90. You-Cheng Hseu, Hsiao-Tung Tsou, K.J. Senthil Kumar, Kai-Yuan Lin, Hsueh-Wei Chang*, Hsin-Ling Yang*. The anti-tumor activity of Antrodia camphorata in melanoma cells: modulation of Wnt/β-catenin signaling pathways. Evidence-Based Complementary and Alternative Medicine 2012, Article ID 197309 (2012) [SCI]
  91. Chao-Neng Tseng, Hsueh-Wei Chang, Joel Stocker, Hui-Chun Wang, Chiu-Chin Lu, Cheng-Hsuan Wu, Jyuer-Ger Yang, Chung-Lung Cho, Hurng-Wern Huang*. A method to identify RNA A-to-I editing targets using I-specific cleavage and exon array analysis. Molecular Cellular Probes 27(1):38-45. Feb. (2013) [SCI]
  92. Hsueh-Wei Chang, Yu-Hsien Chiu, Hao-Yun Kao, Cheng-Hong Yang, and Wen-Hsien Ho. Comparison of classification algorithms with wrapper-based feature selection for predicting osteoporosis outcome based on genetic factors in a Taiwanese women population. International Journal of Endocrinology 2013, Article ID 850735. Feb. (2013) [SCI]
  93. Ching-Yu Yen, Chien-Yang Huang, Ming-Feng Hou, Yi-Hsin Yang, Chao-Hsiang Chang, Hurng-Wern Huang, Chung-Ho Chen*, and Hsueh-Wei Chang*. Evaluating the performance of fibronectin 1 (FN1), integrin alpha 4 beta 1 (ITGA4), syndecan-2 (SDC2), and glycoprotein CD44 as the potential biomarkers of oral squamous cell carcinoma (OSCC). Biomarkers 18(1):63-72. Feb. (2013)[SCI]
  94. Cheng-Hong Yang, Hsueh-Wei Chang, Ming-Cheng Lin and Li-Yeh Chuang*. Improved branch and bound algorithm for detecting SNP-SNP interactions in breast cancer. Journal of Clinical Bioinformatics 3:4 Feb. (2013). [SCI]
  95. Kuan-Jen Chen, Chin-Kai Tseng, Fang-Rong Chang, Jin-Iong Yang, Chi-Chen Yeh, Wei-Chun Chen, Shou-Fang Wu, Hsueh-Wei Chang*, Jin-Ching Lee*. Aqueous extract of the edible Gracilaria tenuistipitata inhibits hepatitis C viral replication via cyclooxygenase-2 suppression and reduces virus-induced inflammation. PLoS One 8(2): e57704. Feb. (2013)[SCI]
  96. Cheng-Hong Yang*, Yu-Huei Cheng*, Li-Yeh Chuang, Hsueh-Wei Chang*. Drug-SNPing: an integrated drug-based, protein interaction-based tagSNP-based pharmacogenomics platform for SNP genotyping. Bioinformatics 29 (6):758-764Feb. (2013) [SCI]
  97. Cheng-Hong Yang, Yu-Da Lin, Li-Yeh Chuang*, Hsueh-Wei Chang*. SNP barcodes generated using particle swarm optimization to detect susceptibility to breast cancer. Natural Science5(3):359-367. Mar. (2013)
  98. Wei-Hsuan Huang, Chao-Neng Tseng, Jen-Yang Tang, Cheng-Hong Yang, Shih-Shin Liang*, Hsueh-Wei Chang*. RNA editing and drug discovery for cancer therapy. ScientificWorldJournal 2013, Apr. Article ID 804505 (2013)[SCI]
  99. Cheng-Hong Yang, Hsueh-Wei Chang, Ho-Yang Lin, and Li-Yeh Chuang. Evaluation of antioxidant and antimicrobial activities from 28 Chinese herbal medicines. Journal of Pharmacognosy and Phytochemistry 2(1):294-305. Apr. (2013)
  100. Jen-Yang Tang, Jin-Ching Lee, Ming-Feng Hou, Chun-Lin Wang, Chien-Chi Chen, Hurng-Wern Huang, Hsueh-Wei Chang*. Alternative splicing for diseases, cancers, drugs, and databases. ScientificWorldJournal 2013, Article ID 703568. May (2013)[SCI]
  101. Chien-Chih Chiu, Jo-Wen Haung, Fang-Rong Chang, Kuang-Jing Huang, Hsuan-Min Huang, Hurng-Wern Huang, Chon-Kit Chou, Yang-Chang Wu*, Hsueh-Wei Chang*. Golden berry-derived 4β-hydroxywithanolide E for selectively killing oral cancer cells by generating ROS, DNA damage, and apoptotic pathways. PLoS One 8(5): e64739. May (2013) [SCI]
  102. Cheng-Hong Yang, Yu-Da Lin, Li-Yeh Chuang, and Hsueh-Wei Chang. Evaluating breast cancer susceptibility using improved genetic algorithms in generating genotype SNP barcodes. IEEE/ACM Transactions on Computational Biology and Bioinformatics 10(2):361-71. Mar-Apr. (2013) [SCI]
  103. Jen-Yang Tang, Jin-Ching Lee, Yung-Ting Chang, Ming-Feng Hou, Chih-Chuang Liaw*, Hsueh-Wei Chang*. Long non-coding RNAs related diseases, cancers and drugs. ScientificWorldJournal 2013, Article ID 943539 (2013)[SCI]
  104. Jin-Ching Lee, Ming-Feng Hou, Hurng-Wern Huang, Fang-Rong Chang, Chi-Chen Yeh, Jen-Yang Tang*, Hsueh-Wei Chang*. Marine algal natural products with anti-oxidative, anti-inflammatory, and anti-cancer properties. Cancer Cell International 2013, 13:55 (2013)[SCI]
  105. Shyh-Jong Wu, Li-Yeh Chuang, Yu-Da Lin, Wen-Hsien Ho, Cheng-Hong Yang*, Hsueh-Wei Chang*. Particle swarm optimization algorithm for analyzing SNP-SNP interaction of renin-angiotensin system genes against hypertension. Molecular Biology Reports 40(7):4227-4233. Jul. (2013)[SCI]
  106. Jen-Yang Tang, Li-Yeh Chuang, Edward Hsi, Yu-Da Lin, Cheng-Hong Yang*, Hsueh-Wei Chang*. Identifying the association rules between clinicopathologic factors and higher survival performance in operation-centric oral cancer patients using the Apriori algorithm. BioMed Research International 2013, Article ID 359634. Jul. (2013) [SCI]
  107. Chao-Neng Tseng, Chung-Lung Cho, Tzan-Wen Chen, Chien-Chih Chiu, Hsueh-Wei Chang, Fang-Rong Chang and Yung-Fu Chang*. Brefeldin A inhibits cancer stem cell properties in human lung cancer cells. Current Signal Transduction Therapy 8(2): 113-118. Aug. (2013[SCI]
  108. Jen-Yang Tang, Hsueh-Wei Chang*, and Jan-Gowth Chang*. Modulating roles of amiloride in irradiation-induced antiproliferative effects in glioblastoma multiforme cells involving Akt phosphorylation and the alternative splicing of apoptotic genes. DNA Cell Biol 32(9):504-510. Sep. (2013)[SCI]
  109. Hsin-Ping Yang, Tsan-Chih Wang, Shiou-Jen Wang, Shih-Ping Chen, Eva Wu, Shao-Qua Lai, Hsueh-Wei Chang*, Chao-Wei Liao*. Recombinant chimeric vaccine composed of PRRSV antigens and truncated Pseudomonas exotoxin A (PE-K13). Research in Veterinary Science 95(2):742-751.Oct. (2013)[SCI]
  110. Jin-Bor Chen, Li-Yeh Chuang, Yu-Da Lin, Chia-Wei Liou, Tsu-Kung Lin, Wen-Chin Lee, Ben-Chung Cheng, Hsueh-Wei Chang*, and Cheng-Hong Yang*. Preventive SNP-SNP interaction analyses in the mitochondrial displacement loop (D-loop) from chronic dialysis patients using an initialization strategy genetic algorithm. Mitochondrion13: 698-704. Nov. (2013) [SCI]
  111. Chao-Neng Tseng, Chien-Fu Huang, Chung-Lung Cho, Hsueh-Wei Chang, Chao-Wei Huang, Chien-Chih Chiu*, Yung-Fu Chang*. Brefeldin A effectively inhibits cancer stem cell properties and MMP-9 activity in human colorectal cancer Colo 205 cells. Molecules 18, 10242-10253. Aug. (2013) [SCI]
  112. Hsueh-Wei Chang*, Li-Yeh Chuang, Sanjay Guleria and Sammia Yasmin. Natural products: Bioactivity, biochemistry, and biological effects in cancer and disease therapy. ScientificWorldJournal 2013, Article ID 713480. Editorial Aug. (2013)[SCI]
  113. Joel Stocker, Hurng-Wern Huang, Hong-Ming Wang, Hsueh-Wei Chang, Chien-Chih Chiu, Chung-Lung Cho, Chao-Neng Tseng*. Reduction of RNA A-to-I editing in Drosophila acclimated to heat shock. Kaohsiung J Med Sci 29:478-83. Sep. (2013) [SCI]
  114. Cheng-Hong Yang, Yu-Da Lin, Li-Yeh Chuang*, Jin-Bor Chen, Hsueh-Wei Chang*. MDR-ER: Balancing functions for adjusting the ratio in risk classes and classification errors for imbalanced cases and controls using multifactor-dimensionality reduction. PLoS One8(11): e79387. Nov. (2013)[SCI]
  115. Hsueh-Wei Chang*. The fate of marine algal natural products-treated cells depend on it ROS modulating effects. Journal of Rashid Latif Medical College 2: 8-10. Dec. (2013)
  116. Jen-Yang Tang, Yong-Yuan Fang, Edward Hsi, Ya-Chun Huang, Nicholas Chung-Heng Hsu, Wen-Chi Yang, Hsueh-Wei Chang, Chee-Yin Chai, Pei-Yi Chu*. Immunopositivity of Beclin-1 and ATG5 as indicators of survival and disease recurrence in oral squamous cell carcinoma. Anticancer Research 33(12):5611-6.Dec. (2013). [SCI]
  117. Chin-Kai Tseng, Chun-Kuang Lin, Hsueh-Wei Chang, Yu-Hsuan Wu, Feng-Lin Yen, Fang-Rong Chang, Wei-Chun Chen, Chi-Chen Yeh, Jin-Ching Lee*. Aqueous extract of Gracilaria tenuistipitata suppresses LPS-induced inflammation via NF-κB and MAPK activation in RAW 264.7 and rat peritoneal macrophages and exerts hepatoprotective effects on carbon tetrachloride-treated ratPLoS One 9(1): e86557. Jan. (2014)[SCI]
  118. Chao-Neng Tseng, Yung-Ting Chang, Hui-Tzu Chiu, Yii-Cheng Chou, Hurng-Wern Huang, Chien-Chung Cheng, Ming-Hui Liao*, Hsueh-Wei Chang*. High-throughput gender identification of penguin species using melting curve analysis. Animal Biotechnology 25(2): 119-127. Feb. (2014) [SCI]
  119. Yu-Huei Cheng, Li-Yeh Chuang, Hsueh-Wei Chang*, Cheng-Hong Yang*. Improved candidate drug mining for Alzheimer’s disease. Biomed Res Int 2014, Article ID 897653. Feb. (2014)[SCI]
  120. Hsueh-Wei Chang, Hui-Jun Wang, Chiau-Yi Chen, Ting-Wei Hung, Ming-Feng Hou, Shyng-Shiou F. Yuan, Chih-Jen Huang*, Chao-Neng Tseng*.  5-Azacytidine induces anoikis, inhibits mammosphere formation and reduces metalloproteinase 9 activity in MCF-7 human breast cancer cells. Molecules 19(3), 3149-3159. Mar. (2014)[SCI]
  121. Wei-Chiao Chang, Yong-Yuan Fang, Hsueh-Wei Chang*, Li-Yeh Chuang, Yu-Da Lin, Ming-Feng Hou*, Cheng-Hong Yang*. Identifying association model for single-nucleotide polymorphisms of ORAI1 gene for breast cancer in a Taiwanese population. Cancer Cell International 2014, 14:29. Mar. (2014). [SCI]
  122. Ammad Ahmad Farooqi*, Ming-Feng Hou, Chien-Chi Chen, Chun-Lin Wang, Hsueh-Wei Chang*. Androgen receptor and gene network: Micromechanics reassemble the signaling machinery of TMPRSS2-ERG positive prostate cancer cells. Cancer Cell International 2014,  14:34 (2014)[SCI]
  123. Cheng-Hong Yang, Yu-Da Lin, Li-Yeh Chuang*, Hsueh-Wei Chang*. Double-bottom chaotic map particle swarm optimization based on chi-square test to determine gene-gene interactions. Biomed Res Int 2014, Article ID 172049. May (2014) [SCI]
  124. Hsien-Yuan Lane, Li-Yeh Chuang, Yu-Da Lin, Ming-Teng Lin, Cheng-Hong Yang*, Hsueh-Wei Chang*. Identification of SNP barcode biomarkers for genes associated with facial emotion perception using particle swarm optimization algorithm. Annals of General Psychiatry 2014, 13:15. May (2014)[SCI]
  125. Jin-Bor Chen, Li-Yeh Chuang, Yu-Da Lin, Chia-Wei Liou, Tsu-Kung Lin, Wen-Chin Lee, Ben-Chung Cheng, Hsueh-Wei Chang*, and Cheng-Hong Yang*. Genetic algorithm-generated SNP barcodes of the mitochondrial D-loop for chronic dialysis susceptibility. Mitochondrial DNA 25(3): 231-237. Jun. (2014)[SCI]
  126. Ruei-Nian Li, Chin-Jen Wu, Zong-Jing Yu, Hsueh-Wei Chang*, Shih-Shin Liang*. Networks development between nicotinic chemical probes and Ca9-22 oral cancer cells by general proteomics analyses. Electrophoresis35(15): 2213-2221. Aug. (2014)[SCI]
  127. Bao-Jueng Wu, Chien-Chih Chiu, Chun-Lin Chen, Wen-Der Wang, Jia-Hong Wang, Zhi-Hong Wen, Wangta Liu, Hsueh-Wei Chang, Chang-Yi Wu*. Nuclear receptor subfamily 2 group F member 1a (nr2f1a) is required for vascular development in zebrafish. PLoS One9(8): e105939. Aug. (2014)[SCI]
  128. Hurng-Wern Huang, Yi-An Chung, Hsun-Shuo Chang, Jen-Yang Tang, Ih-Sheng Chen*, Hsueh-Wei Chang*. Antiproliferative effects of methanolic extracts of Cryptocarya concinna Hance roots on oral cancer Ca9-22 and CAL 27 cell lines involving apoptosis, ROS induction and mitochondrial depolarization. Scientific World Journal 2014: Article ID 180462 (2014)[SCI]
  129. Chih-Jen Huang, Shi-Long Lian, Ming-Feng Hou, Chee-Yin Chai, Yi-Hsing Yang, Sheng-Fung Lin*, Hsueh-Wei Chang*. SNP 1772 C> T of HIF-1α gene associates with breast cancer risk in a Taiwanese population. Cancer Cell International 2014, 14:87. Oct.(2014)[SCI]
  130. Ammad Ahmad Farooqi*, Ilhan Yaylim, Nazlı Ezgi Ozkan, Farrukh Zaman, Hsueh-Wei Chang*. Restoring TRAIL mediated signaling in ovarian cancer cells. Arch. Immunol. Ther. Exp. 62(6):459-74. Dec. (2014)[SCI]
  131. Cheng-Hong Yang, Yu-Da Lin, Li-Yeh Chuang*, and Hsueh-Wei Chang*. DBM-PSO-based SNP-SNP interaction of DNA repair genes in simulated breast cancer association study. Journal of Bioinformatics Research Studies 1(1): 3. (2014).
  132. Chao-Neng Tseng, Yi-Ren Hong, Hsueh-Wei Chang, Tsai-Jung Yu, Ting-Wei Hung, Ming-Feng Hou, Shyng-Shiou F.  Yuan, Chung-Lung Cho, Chien-Tsung Liu, Chien-Chih Chiu, Chih-Jen Huang*. Brefeldin A reduces anchorage- independent survival, cancer stem cell potential and migration of MDA-MB-231 human breast cancer stem cells. Molecules2014, 19, 17464-17477. (2014)[SCI]
  133. Ammad Ahmad Farooqi, Sundas Fayyaz, Ming-Feng Hou, Kun-Tzu Li, Jen-Yang Tang*, Hsueh-Wei Chang*. Reactive oxygen species and autophagy modulation in non-marine drugs and marine drugs. Marine Drugs 12, 5408-5424. Nov. (2014) [SCI]
  134. Yii-Huei Yen, Ammad Ahmad Farooqi, Kun-Tzu Li, Ghazala Butt, Jen-Yang Tang, Chang-Yi Wu, Yuan-Bin Cheng, Ming-Feng Hou*, Hsueh-Wei Chang*. Methanolic extracts of Solieria robusta inhibits proliferation of oral cancer Ca9-22 cells via apoptosis and oxidative stress. Molecules 19, 18721-18732. Nov. (2014) [SCI]
  135. Bing-Hung Chen, Hsuan-Min Huang, Hurng-Wern Huang, Hsueh-Wei Chang*. Grape seed extracts protect against H2O2-induced DNA damage. Pakistan Journal of Clinical and Biomedical Research2(1): 14-15. Short communication. Jan-Jun. (2014)
  136. Chi-Chen Yeh, Hurng-Wern Huang, Chia-Chuan Chung, Shyng-Shiou F. Yuan, Fang-Rong Chang*, Hsueh-Wei Chang*. Antioxidant potential of solvent partitioned extraction from aqueous extract of Gracilaria tenuistipitataCurrent Organic Chemistry 19(1):39-44. Jan. (2015)[SCI]
  137. Shu-Hung Huang, Yun-Nan Lin, Su-Shin Lee, Chee-Yin Chai, Hsueh-Wei Chang, Tsai-Ming Lin, Chung-Sheng Lai, Sin-Daw Lin*. New adipose tissue formation by human adipose derived stem cells with hyaluronic acid gel in immunodeficient mice. Int J Med Sci 12:154-162. Jan. (2015) [SCI]
  138. Fu Ou-Yang, Yu-Da Lin, Li-Yeh Chuang, Hsueh-Wei Chang*, Cheng-Hong Yang*, Ming-Feng Hou*. The combinational polymorphisms of ORAI1 gene are associated with preventive models of breast cancer in the Taiwanese. Biomed Res Int 2015: 281263. Jan. (2015) [SCI]
  139. Wen-Chin Lee, Lung-Chih Li, Jin-Bor Chen*, Hsueh-Wei Chang*. Indoxyl sulfate-induced oxidative stress, mitochondrial dysfunction and biogenesis are partly protected by vitamin C and N-acetylcysteine. Scientific World Journal 2015: Article ID 620826.Mar. (2015).
  140. Ching-Yu Yen, Ming-Feng Hou, Zhi-Wen Yang, Jen-Yang Tang, Kun-Tzu Li, Hurng-Wern Huang, Yu-Hsuan Huang, Sheng-Yang Lee, Tzu-Fun Fu, Che-Yu Hsieh, Bing-Hung Chen,*, Hsueh-Wei Chang*. Concentration effects of grape seed extracts in anti-oral cancer cells involving differential apoptosis, oxidative stress, and DNA damage. BMC Complementary and Alternative Medicine 15: 94 Mar. (2015) [SCI]
  141. Cheng-Hong Yang, Yu-Da Lin, Li-Yeh Chuang*, Hsueh-Wei Chang*. A systematic gene-gene and gene-environment interaction analysis of DNA repair genes XRCC1, XRCC2, XRCC3, XRCC4, and oral cancer risk. OMICS 19(4):238-247. Apr.(2015)[SCI]
  142. Jen-Yang Tang, Edward Hsi, Ya-Chun Huang, Nicholas Chung-Heng Hsu, Wen-Chi Yang, Hsueh-Wei Chang, Chee-Yin Chai, Pei-Yi Chu. Overexpression of autophagy-related 16-like 1 in patients with oral squamous cell carcinoma. Pathology Oncology Research 21:301-305. Apr. (2015)[SCI]
  143. Cheng-Hong Yang, Yu-Da Lin, Shyh-Jong Wu*, Li-Yeh Chuang*, Hsueh-Wei Chang*. High order gene-gene interactions in eight single nucleotide polymorphisms of renin-angiotensin system genes for hypertension association study. Biomed Res Int 2015, Article ID 454091.Apr. (2015) [SCI]
  144. Hsueh-Wei Chang*, Shao-Yu Chen, Li-Yeh Chuang, Sanjay Guleria. Toxicology and disease/cancer therapy in reactive oxygen species-mediated drugs and treatments. ScientificWorldJournal 2015, 860563. Apr. (2015) [SCI]
  145. Ammad Ahmad Farooqi, Jen-Yang Tang, Ruei-Nian Li, Muhammad Ismail, Yung-Ting Chang, Chih-Wen Shu, Shyng-Shiou F. Yuan, Jing-Ru Liu, Chih-Jen Huang*, Hsueh-Wei Chang*. Epigenetic mechanisms in cancer: push and pull between kneaded erasers and fate writers. International Journal of Nanomedicine 10: 3183-3191. May (2015)[SCI]
  146. Jen-Yang Tang, Ruei-Nian Li, Ping-Ho Chen, Hurng-Wern Huang, Ming-Feng Hou*, Hsueh-Wei Chang*. Alternative splicing, DNA damage, and modulating drugs in radiation therapy for cancer. Anti-Cancer Agents in Medicinal Chemistry 15(6): 674-680. June (2015) [SCI]
  147. Kun-Tzu Li and Hsueh-Wei Chang*. 20-year-old nitrocellulose paper and PVDF membranes for western blotting. Journal of Rashid Latif Medical College 4(1): 1-2. Jan-Jun. (2015)
  148. Ammad Ahmad Farooqi, Kun-Tzu Li, Sundas Fayyaz, Yung-Ting Chang, Muhammad Ismail, Chih-Chuang Liaw, Shyng-Shiou F. Yuan, Jen-Yang Tang*, Hsueh-Wei Chang*. Anticancer drugs for the modulation of endoplasmic reticulum stress and oxidative stress. Tumor Biology 36:5743-5752. Aug. (2015) [SCI]
  149. Ammad Ahmad Farooqi, Shyh-Jong Wu, Yung-Ting Chang, Jen-Yang Tang, Kun-Tzu Li, Muhammad Ismail, Chih-Chuang Liaw, Ruei-Nian Li*, Hsueh-Wei Chang*. Activation and inhibition of ATM by phytochemicals: awakening and sleeping the guardian angel naturally. Archivum Immunologiae et Therapiae Experimentalis 63:357-366. Oct. (2015) [SCI]
  150. Ammad Ahmad Farooqi, Ruei-Nian Li, Hurng-Wern Huang, Muhammad Ismail, Shyng-Shiou F. Yuan, Hui-Min David Wang, Jing-Ru Liu, Jen-Yang Tang*, Hsueh-Wei Chang*. Natural products mediated regulation of oxidative stress and DNA damage in ultraviolet exposed skin cells. Current Pharmaceutical Biotechnology 16(12):1078-84. (2015)[SCI]
  151. Hsueh-Wei Chang*. Selective killing natural products and drugs in oral cancer treatments. Dental Research and Management1: 1-2. (editorial) (2015)
  152. I-Fei Huang, I-Chun Lin, Pei-Feng Liu, Ming-Fang Cheng, Yen-Chen Liu, Yao-Dung Hsieh, Jih-Jung Chen, Chun-Lin Chen, Hsueh-Wei Chang* and Chih-Wen Shu*. Lactobacillus acidophilus attenuates Salmonella-induced intestinal inflammation via TGF-β signalingBMC Microbiology2015, 15:203. Oct. (2015)[SCI]
  153. Chien-Chih Chiu*, Han-Lin Chou, Bing-Hung Chen, Kuo-Feng Chang, Chih-Hua Tseng, Yao Fong, Tzu-Fun Fu, Hsueh-Wei Chang, Chang-Yi Wu, Eing-Mei Tsai, Shinne-Ren Lin and Yeh-Long Chen*. BPIQ, a novel synthetic quinoline derivative, inhibits growth and induces mitochondrial apoptosis of lung cancer cells in vitro and in zebrafish xenograft model. BMC Cancer 2015, 15: 962. Dec. (2015)[SCI]
  154. Ching-Yu Yen, Hurng-Wern Huang, Chih-Wen Shu, Ming-Feng Hou, Shyng-Shiou F. Yuan, Hui-Ru Wang, Yung-Ting Chang, Ammad Ahmad Farooqi, Jen-Yang Tang*, Hsueh-Wei Chang*. DNA methylation, histone acetylation and methylation of epigenetic modifications as a therapeutic approach for cancersCancer Letters373 (2):185-192. Apr. (2016)[SCI]
  155. Sin-Daw Lin, Shu-Hung Huang, Yun-Nan Lin, Sheng-Hua Wu, Hsueh-Wei Chang, Tsai-Ming Lin, Chee-Yin Chai, Dar-Jen Hsieh, Kao-Ping Chang. Injected implant of uncultured stromal vascular fraction loaded onto a collagen gel: In vivo study of adipogenesis and long-term outcomes. Ann Plast Surg 76 Suppl 1:S108-116. Mar. (2016) [SCI]
  156. Hsun-Shuo Chang#, Jen-Yang Tang# (co-first), Ching-Yu Yen, Hurng-Wern Huang, Yi-An Chung, Chang-Yi Wu, Ih-Sheng Chen, Ming-Yii Huang*, Hsueh-Wei Chang*. Antiproliferation of Cryptocarya concinna-derived cryptocaryone against oral cancer cells involving apoptosis, oxidative stress, and DNA damage.BMC Complementary and Alternative Medicine 16(1): 94. Mar. (2016) [SCI]
  157. Hsueh-Wei Chang, Jen-Yang Tang, Ching-Yu Yen, Hsun-Shuo Chang, Hurng-Wern Huang, Yi-An Chung, Ih-Sheng Chen, Ming-Yii Huang*. Synergistic anti-oral cancer effects of UVC and methanolic extracts of Cryptocarya concinna roots via apoptosis, oxidative stress and DNA damage. International Journal of Radiation Biology92(5):263-272. May. (2016) [SCI]
  158. Jing-Iong Yang, Jen-Yang Tang, Ya-Sin Liu, Hui-Ru Wang, Sheng-Yang Lee, Ching-Yu Yen*, Hsueh-Wei Chang*. Roe protein hydrolysates of giant grouper (Epinephelus lanceolatus) inhibit cell proliferation of oral cancer cells involving apoptosis and oxidative stress.Biomed Res Intl2016, Article ID 8305073 Apr. (2016) [SCI]
  159. Chi-Chen Yeh, Kun-Tzu Li, Jen-Yang Tang, Hui-Ru Wang, Jing-Ru Liu, Hurng-Wern Huang, Fang-Rong Chang, Cheng-En Tasi, I-Wen Lo, Ming-Yii Huang*, Hsueh-Wei Chang*. Butanol-partitioned extraction from aqueous extract of Gracilaria tenuistipitata inhibits cell proliferation of oral cancer cells involving apoptosis and oxidative stress. DNA and Cell Biology 35(5):210-216. May (2016) [SCI]
  160. Yung-Ting Chang, Chiung-Yao Huang, Kun-Tzu Li, Chih-Chuang Liaw, Ruei-Nian Li, Jing-Ru Liu, Shih-Hsiung Wu, Jyh-Horng Sheu*, Hsueh-Wei Chang*. Sinuleptolide inhibits proliferation of oral cancer Ca9-22 cells involving apoptosis, oxidative stress, and DNA damage. Archieves of Oral Biology 66:147-154.(2016) June [SCI]
  161. Fu Ou-Yang, Hsueh-Wei Chang, Yu-Da Lin, Li-Yeh Chuang, Ming-Hong Hou*, Cheng-Hong Yang*. Breast cancer-associated high-order SNP-SNP interaction of CXCL12/CXCR4-related genes by an improved multifactor dimensionality reduction (MDR-ER). Oncology Reports 36: 1739-1747.Sept. (2016) [SCI]
  162. Chih-Wen Shu, Hong-Tai Chang, Chieh-Shan Wu, Chien-Hsun Chen, Sam Wu, Hsueh-Wei Chang, Soong-Yu Kuo, Earl Fu, Pei-Feng Liu*, Yao-Dung Hsieh*. RelA-mediated BECN1 expression is required for reactive oxygen species-induced autophagy in oral cancer cells exposed to low-power laser irradiation. PLoS One 11, e0160586. Sep. (2016) [SCI]  

  163. Wen-Chin Lee, Chien-Hua Chiu, Jin-Bor Chen*, Chiu-Hua Chen, Hsueh-Wei Chang*. Mitochondrial fission increases apoptosis and decreases autophagy in renal proximal tubular epithelial cells treated with high glucose. DNA and Cell Biol 35(11): 657-665. Nov. (2016) [SCI]

  164. Chung-Yi Chen, Ching-Yu Yen, Hui-Ru Wang, Hui-Ping Yang, Jen-Yang Tang, Shih-Hsien Hsu*, Hsueh-Wei Chang*. Tenuifolide B from Cinnamomum tenuifolium stem inhibits proliferation of oral cancer cells via apoptosis, ROS generation, mitochondrial depolarization, and DNA damage. Toxins 2016, 8(11), 319. Nov. (2016) [SCI]

  165. Cheng-Hong Yang, Sin-Hua Moi, Li-Yeh Chuang, Shyng-Shiou F. Yuan, Ming-Feng Hou, Yi-Chen Lee*, Hsueh-Wei Chang*. Interaction of MRE11 and clinicophathological characteristics in recurrence of breast cancer: Individual and cumulated receiver operating characteristic analyses. Biomed Res Intl 2017, Article ID 2563910 Jan. (2017) [SCI]

  166. Hsueh‐Wei Chang#, Wen‐Der Wang# (#co-first), Chien‐Chih Chiu, Chiou‐Hua Chen, Yi‐Shan Wang, Zih‐Ying Chen, Wangta Liu, Ming‐Hong Tai, Zhi‐Hong Wen,Chang‐Yi Wu*. Ftr82 is critical for vascular patterning during zebrafish development. International Journal of Molecular Sciences 18(1): 156. Jan. (2017) [SCI]

  167. Yung-Ting Chang, Chiung-Yao Huang, Ruei-Nian Li, Chih-Chuang Liaw, ing-Ru Liu, Jyh-Horng Sheu*, Hsueh-Wei Chang*. N-acetylcysteine rescues soft corals-derived sinuleptolide-induced antiproliferation and DNA damage in oral cancer cells. OncoTargets and Therapy 10:3289–3297. July (2017)[SCI]

  168. Huang PC, Chiu CC, Chang HW, Wang YS, Syue HH, Song YC, Weng ZH, Tai MH, Wu CY. Prdx1-encoded peroxiredoxin is important for vascular development in zebrafish. FEBS Lett 591(6): 889-902. Mar. (2017)[SCI]

  169. Ching-Yu Yen, Shyun-Yeu Liu, I-Jung Feng, Yu-Wei Wu, Ching-Yuan Chen, Chao-Nan Hsiung, Hsueh-Wei Chang, Che-Yi Lin, Min-Te Chang, His-Chien Yu, Sheng-Yang Lee*. The implication for the second primary cancer from visible oral and oropharyngeal premalignant lesions in betel-nut chewing related oral cancer patients. Head & Neck 39(7): 1428-35. July (2017)[SCI]

  170. Cheng-Hong Yang, Kuo-Chuan Wu, Hans-Uwe Dahms, Li-Yeh Chuang*, Hsueh-Wei Chang*. SNP barcoding of COI sequences for discriminating 17 Columbidae birds by decision tree algorithm. Ecology and Evolution 7(13): 4717-4725. July (2017)[SCI] 

  171. Ammad Ahmad Farooqi, Chih-Wen Shu, Hurng-Wern Huang, Hui-Ru Wang, Yung-Ting Chang, Sundas Fayyaz, Shyng-Shiou F. Yuan, Jen-Yang Tang*, Hsueh-Wei Chang*. TRAIL, Wnt, sonic hedgehog, TGFβ, and miRNA signalings are potential targets for oral cancer therapy. Int J Mol Sci 18(7): 1523. July (2017)[SCI]

  172. Hui-Min Wang, Hsin-Ling Yang, Varadharajan Thiyagarajan, Tzu-Hsiang Huang, Pei-Jane Huang, Ssu-Ching Chen, Jer-Yuh Liu, Li-Sung Hsu, Hsueh-Wei Chang, You-Cheng Hseu*. Coenzyme Q0 enhances ultraviolet B-induced apoptosis in human estrogen receptor-positive breast (MCF-7) cancer cells. Integrative Cancer Therapies 16(3):385-396. Sept. (2017)[SCI]

  173. Yung-Ting Chang, Chang-Yi Wu, Jen-Yang Tang, Chiung-Yao Huang, Chih-Chuang Liaw, Shih-Hsiung Wu, Jyh-Horng Sheu*, Hsueh-Wei Chang*. Sinularin induces oxidative stress-mediated G2/M arrest and apoptosis in oral cancer cells. Environmental Toxicology 32(9):2124-2132. Sept. (2017)[SCI]

  174. Cheng-Hong Yang, Yu-Shiun Lin, Li-Yeh Chuang*, Hsueh-Wei Chang*. A particle swarm optimization-based approach with local search for predicting protein folding. J Computational Biology 24(10):981-994. Oct. (2017) [SCI] 
  175. Chung-Yi Chen, Ching-Yu Yen, Gao-Mai Shen, Tzu-Jung Yu, Yi-Shin Liao, Ru-In Jian, Sheng-Chieh Wang, Jen-Yang Tang*, Hsueh-Wei Chang*. Antioxidant effects of fractions for unripe fruits of Capsicum annuum L. var. conoides. Anti-Cancer Agents in Medicinal Chemistry 17(14): 1971-1977. Apr. (2017)[SCI] 

  176. Cheng-Hong Yang, Yu-Da Lin, Li-Yeh Chuang*, Jin-Bor Chen*, Hsueh-Wei Chang*. Joint analysis of SNP-SNP-environment interactions for chronic dialysis by an improved branch and bound algorithm. J Computational Biology 24(12): 1212-1225. Dec. (2017) [SCI]

  177. Hsueh-Wei Chang, Ruei-Nian Li, Hui-Ru Wang, Jing-Ru Liu, Jen-Yang Tang, Hurng-Wern Huang, Yu-Hsuan Chan, Ching-Yu Yen*. Withaferin A induces oxidative stress-mediated apoptosis and DNA damage in oral cancer cells. Frontiers in Physiology 8: 643. Sept. (2017) [SCI]
  178. Chien-Juan Chen, Hsueh-Wei Chang, Cheng-Hong Yang, Hung-Yi Chuang*, Hsin-Su Yu. Use of genetic algorithm combinational single-nucleotide polymorphisms could modify the association of blood lead levels and bone matrix density. Epidemiology 28 Suppl 1: S121-S5. Oct. (2017) [SCI]
  179. Pei-Feng Liu, Chien-Jen Hsu, Wei-Lun Tsai, Jin-Shiung Cheng, Jih-Jung Chen, I-Fei Huang, Ho-Hsing Tseng, Hsueh-Wei Chang*, Chih-Wen Shu*. Ablation of ATG4B suppressed autophagy and activated AMPK for cell cycle arrest in cancer cells. Cellular Physiology and Biochemistry 44(2):728-740. Dec.(2017) [SCI]
  180. Pei-Feng Liu, Kun-Lin Tsai, Chien-Jen Hsu, Wei-Lun Tsai, Jin-Shiung Cheng, Hsueh-Wei Chang, Chung-Wai Shiau, Yih-Gang Goan, Ho-Hsing Tseng, Chih-Hsuan Wu, John C. Reed, Lee-Wei Yang*, Chih-Wen Shu*. Drug repurposing screening identifies tioconazole as an ATG4 inhibitor that suppresses autophagy and sensitizes cancer cells to chemotherapy. Theranostics 8(3): 830-845. (2018) [SCI]
  181. Sin-Hua Moi#, Yi-Chen Lee#, Li-Yeh Chuang, Shyng-Shiou F. Yuan, Fu Ou-Yang, Ming-Feng Hou, Cheng-Hong Yang*, Hsueh-Wei Chang*. Cumulative receiver operating characteristic for analyzing interaction between tissue visfatin and clinicopathologic factors in breast cancer progression. Cancer Cell International 18:19. Feb. (2018) [SCI]
  182. Jen-Yang Tang#, Hurng-Wern Huang#, Hui-Ru Wang, Ya-Ching Chan, Jo-Wen Huang, Chih-Wen Shu, Yang-Chang Wu*, Hsueh-Wei Chang*. 4β-hydroxywithanolide E selectively induces oxidative DNA damage for selective killing against oral cancer cells. Environmental Toxicology 33(3): 295-304. Feb. (2018) [SCI]
  183. Cheng-Hong Yang, Kuo-Chuan Wu, Li-Yeh Chuang*, Hsueh-Wei Chang*. Decision tree algorithm-generated SNP barcodes of rbcL genes for 38 Brassicaceae species tagging. Evolutionary Bioinformatics 14:1-19. Mar. (2018) [SCI]
  184. Cheng-Hong Yang, Yu-Shiun Lin, Sin-Hua Moi, Kuo-Chuan Wu, Li-Yeh Chuang*, Hsueh-Wei Chang*. Hybrid high exploration particle swarm optimization algorithm improves the prediction of the 2-dimensional hydrophobic-polar model for protein folding. Current Bioinformatics 13(2): 182-192.Apr. (2018) [SCI]
  185. Hurng-Wern Huang#, Jen-Yang Tang#, Fu Ou-Yang, Hui-Ru Wang, Pei-Ying Guan, Chiung-Yao Huang, Chung-Yi Chen, Ming-Feng Hou, Jyh-Horng Sheu*, Hsueh-Wei Chang*. Sinularin selectively kills breast cancer cells showing G2/M arrest, apoptosis, and oxidative DNA damage. Molecules 23: 849. Apr. (2018) [SCI]
  186. Cheng-Hong Yang, Kuo-Chuan Wu, Yu-Shiun Lin, Li-Yeh Chuang*, Hsueh-Wei Chang*. Solving protein folding problem with ions motion optimization and greedy algorithms. BioData Mining 11:17. Aug. (2018) [SCI]
  187. Jia-Feng Chang, Shih-Shin Liang, Pounraj Thanasekaran, Hsueh-Wei Chang, Li-Li Wen, Chung-Hua Chen, Jian-Chiun Liou, Jih-Chen Yeh, Shih-Hao Liu, Huei-Min Dai, Wei-Ning Lin*. Translational medicine in pulmonary-renal crosstalk: Therapeutic targeting of p-cresyl sulfate triggered nonspecific ROS and chemoattractants in dyspneic patients with uremic lung injury. Journal of Clinical Medicine 2018: 7, 266. Sept. (2018) [SCI]
  188. Hsueh-Wei Chang, Ching-Yu Yen, Chung-Ho Chen, Jun-Hsu Tsai, Jen-Yang Tang, Yung-Ting Chang, Hurng-Wern Huang, Yu-Hsun Kao, Shyng-Shiou F. Yuan, Yen-Yun Wang, Sheng-Yang Lee*. Evaluation of the integrins α3, α5, β1 and β6 as tumor markers of oral squamous cell carcinoma. Oncology Letters 16(4):4773-4781. Oct. (2018) [SCI]
  189. Jen-Yang Tang, Chang-Yi Wu, Chih-Wen Shu, Sheng-Chieh Wang, Meng-Yang Chang*, Hsueh-Wei Chang*. A novel sulfonyl chromen-4-ones (CHW09) preferentially kills oral cancer cells involving apoptosis, oxidative stress, and DNA damage.Environmental ToxicologyDOI: 10.1002/tox.22625(2018) [SCI]
  190. Pei-Feng Liu†, Hsueh-Wei Chang† (co-first), Jin-Shiung Cheng, Huai-Pao Lee, Ching-Yu Yen, Wei-Lun Tsai, Jiin-Tsuey Cheng, Yi-Jing Li, Wei-Chieh Huang, Cheng-Hsin Lee, Luo-Pin Ger and Chih-Wen Shu*. Map1lc3b and Sqstm1 modulated autophagy for tumorigenesis and prognosis in certain subsites of oral squamous cell carcinoma. Journal of Clinical Medicine 7: 478. Nov. (2018) [SCI]
  191. Cheng-Hong Yang, Kuo-Chuan Wu, Li-Yeh Chuang*, Hsueh-Wei Chang*. Decision theory-based COI SNP tagging approach for 126 Scombriformes species tagging. Front Genet 10: 259. Apr. (2019) [SCI]
  192. Hsueh-Wei Chang#, Pei-Feng Liu# (#co-first), Wei-Lun Tsai, Wan-Hsiang Hu, Yu-Chang Hu, Hsiu-Chen Yang, Wei-Yu Lin, Jing-Ru Weng*,Chih-Wen Shu*. Toxins 2019;11(6):313 Jun. (2019) [SCI]
  193. Jen-Yang Tang, Yi-Hua Xu, Li-Ching Lin, Fu Ou-Yang, Kuang-Han Wu, Li-Yi Tsao, Tzu-Jung Yu, Hurng-Wern Huang, Hui-Ru Wang, Wangta Liu*, Hsueh-Wei Chang*. LY303511 displays antiproliferation potential against oral cancer cells in vitro and in vivo. Environmental Toxicology34(8):958-967. Aug.(2019) [SCI]
  194. Jen-Yang Tang, Sheng-Yao Peng, Yuan-Bin Cheng, Chun-Lin Wang, Ammad Ahmad Farooqi, Tzu-Jung Yu, Ming-Feng Hou, Sheng-Chieh Wang, Chia-Hung Yen, Leong-Perng Chan, Fu Ou-Yang*, Hsueh-Wei Chang*. Ethyl acetate extract of Nepenthes adrianii x clipeata induces antiproliferation, apoptosis and DNA damage against oral cancer cells through oxidative stress. Environmental Toxicology 34(8):891-901. Aug. (2019) [SCI]
  195. Jen-Yang Tang, Li-Jie Li, Fu Ou-Yang, Chun-Lin Wang, Chih-Wen Shu, Kuang-Han Wu, Hui-Ru Wang, Chia-Hung Yen, Yuan-Bin Cheng*, Hsueh-Wei Chang*. Ethyl acetate extract of Nepenthes ventricosa x maxima exerts preferential killing to oral cancer cells. DNA Cell Biology38(8):763-772. Aug. (2019) [SCI]
  196. Jen-Yang Tang, Tzu-Jung Yu, Li-Ching Lin, Sheng-Yao Peng, Chun-Lin Wang, Fu Ou-Yang, Yuan-Bin Cheng*, Hsueh-Wei Chang*. Ethyl acetate leave extract of Nepenthes ventricosa x sibuyanensis inhibits ROS-mediated proliferation against oral cancer cells. OncoTargets and Therapy 12: 5227-5239. July (2019) [SCI]
  197. Yih-Gang Goan, Pei-Feng Liu, Hsueh-Wei Chang, Hung-Chih Chen, Wen-Chih Chen, Shyh Ming Kuo, Cheng-Hsin Lee, Chih-Wen Shu *. Kinome-wide screening with small interfering RNA identified polo-like kinase 1 as a key regulator of proliferation in oral cancer cells. Cancers 11(8), 1117 (2019) [SCI]
  198. Ping-Ho Chen, Li-Yeh Chuang, Kuo-Chuan Wu, Yan-Hsiung Wang, Tien-Yu Shieh, Jim Jinn-Chyuan Sheu, Hsueh-Wei Chang*, Cheng-Hong Yang*. Application of simulation-based CYP26 SNP-environment barcodes for evaluating the occurrence of oral malignant disorders by odds ratio-based binary particle swarm optimization: A case-control study in the Taiwanese population. Plos One 14(8): e0220719. Aug. (2019) [SCI]
  199. Jen-Yang Tang, Chih-Wen Shu, Chun-Lin Wang, Sheng-Chieh Wang, Meng-Yang Chang, Li-Ching Lin*, Hsueh-Wei Chang*. Sulfonyl chromen-4-ones (CHW09) shows an additive effect to inhibit cell growth of X-ray irradiated oral cancer cells, involving apoptosis and ROS generation. Int J Radiation Biol95(9): 1226-1235. Sept. (2019) [SCI]
  200. Hui-Ru Wang, Jen-Yang Tang, Yen-Yun Wang, Ammad Ahmad Farooqi, Ching-Yu Yen, Shyng-Shiou F. Yuan, Hurng-Wern Huang*, Hsueh-Wei Chang*. Manoalide preferentially kills oral cancer cells by oxidative stress-mediated apoptosis and DNA damage. Cancers 11(9): 1303 Sept. (2019) [SCI]
  201. Jen-Yang Tang, Fu Ou-Yang, Ming-Feng Hou, Hurng-Wern Huang, Hui-Ru Wang, Kun-Tzu Li, Sundas Fayyaz, Chih-Wen Shu*, Hsueh-Wei Chang*. Oxidative stress-modulating drugs have preferential anticancer effects - involving the regulation of apoptosis, DNA damage, endoplasmic reticulum stress, autophagy, metabolism, and migration. Seminars in Cancer Biology 58:109-117. Oct. (2019) [SCI]

 

update 20191016-hwc

image

imagePatents

1. Hsueh-Wei Chang*, Chien-Chung Cheng, De-Luen Gu, Chun-An Cheng, Cheng-Hao Wen. Method for eagles gender identification and Chromo- Helicase-DNA binding protein gene sequence of Spilornis cheela hoya. Taiwan patent No. I326712. (2010/07/01-2027/09/25) 

2. Hsueh-Wei Chang*, Chien-Chung Cheng, De-Luen Gu, San-Hua Su. Method for gender identification of eagles with probe-based real-time PCR and the sequences used for gender identification of eagles. (US patent US8158358 B2) (2012/04/17 to 2030/05/08)

3. Hsueh-Wei Chang, Chien-Chung Cheng, Ying-Fang Su, and Yu-Chen Hung. Method for Columbidae gender identification, nucleotide sequence for Columbidae gender and nucleotide primer pair for Columbidae gender. US patent US8420316B2 (2013/04/16 to 2031/05/09)

4. Hsueh-Wei Chang, Fang-Rong Chang, Jin-Ching Lee, Chi-Chen Yeh. Cancer cell growth inhibiting, cancer cell apoptosis inducing and cancer cell DNA damage causing pharmaceutical composition, and uses of Gracilaria spp. alcohol extract. Taiwan patent no. I458486 (2014/11/01-2033/02/26)

5. Hsueh-Wei Chang, Chien-Chung Cheng, Ying-Fang Su, Yu-Chen Hung. Method for Columbidae gender identification, nucleotide sequence for Columbidae gender and nucleotide primer pair for Columbidae gender. Taiwan patent no. I472623 (2015/02/11-2030/03/30)

6. Hsueh-Wei Chang,Yang-Chang Wu, Fang-Rong Chang, Chien-Chih Chiu, Jo-Wen Haung, Kuang-Jing Huang, Hsuan-Min Huang. The application of selective killing of oral cancer cells involving 4β-hydroxywithanolide. Taiwan patent no. I475987 (2015/03/11-2033/05/05)

7. Jing-Iong Yang, Hsueh-Wei Chang, Chao-Neng Tseng, Jin-Ching Lee,林志遠、Chi-Chen Yeh. Free radical-induced intracellular DNA damage reducing reagent, medicament or health food and skin care product or cosmetics, and uses of Gracilaria spp. extract. Taiwan patent no. I492766 (2015/07/21-2031/01/20)

8. Hsueh-Wei Chang, Yung-Ting Chang, Hui-Tzu Chiu. Method for Spheniscidae gender identification, nucleotide sequence for Spheniscidae gender and nucleotide primer pair for Spheniscidae gender. Taiwan patent no. I524067 (2016/03/01-2031/11/07)

9. Hsueh-Wei Chang, Chao-Neng Tseng, Yu-Shiuan Liu. Method for Phasianidae gender identification, nucleotide sequence for Phasianidae gender and nucleotide primer pair for Phasianidae gender. Taiwan patent no. I534269 (2016/05/21 -2031/10/26)

10. Hsueh-Wei Chang, Hsun-Shuo Chang, Ming-Yii Huang, Jen-Yang Tang, Ih-Sheng Chen. Pharmaceutical composition and use of the active ingredient thereof. Taiwan patent no. I577376 (2017/04/11 -2036/08/25)

11. Hsueh-Wei Chang, Chung-Yi Chen, Shih-Hsien Hsu, Jen-Yang Tang, Hui-Ping Yang, Hui-Ru Wang. The application of selective killing of oral cancer cells involving Tenuifolide B. Taiwan patent no. I621433 (2018/04/21 -2036/05/19)

12. Hsueh-Wei Chang, Hsun-Shuo Chang, Ming-Yii Huang, Jen-Yang Tang, Ih-Sheng Chen. Use of Cyrptocarya plant root extract in the manufacture of a medicament for cancer treatment. Taiwan patent no. I644679 (2018/12/21-2036/08/15)

 

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